Primary Site >> Colorectal Cancer
Gene >> S100A4
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Ref: Increased expression of S100A4, a metastasis-associated gene, in human colorectal adenocarcinomas. PMID: 9815629 |
Ref: Increased expression of S100A6 at the invading fronts of the primary lesion and liver metastasis in patients with colorectal adenocarcinoma. PMID: 10952782 |
Ref: Development and progression of malignancy in human colon tissues are correlated with expression of specific Ca(2+)-binding S100 proteins. PMID: 11510959 |
Ref: S100A4 (p9Ka) protein in colon carcinoma and liver metastases: association with carcinoma cells and T-lymphocytes. PMID: 11875708 Ref: Identification of genes differentially expressed in V79 cells grown as multicell spheroids. PMID: 12065053 Ref: Prognostic significance of calcium-binding protein S100A4 in colorectal cancer. PMID: 12404222 |
Ref: Impact of p53 knockout and topotecan treatment on gene expression profiles in human colon carcinoma cells: a pharmacogenomic study. PMID: 12782583 Ref: Nuclear localization of the metastasis-related protein S100A4 correlates with tumour stage in colorectal cancer. PMID: 12898594 |
Ref: Immunofluorometric assay for the metastasis-related protein S100A4: release of S100A4 from normal blood cells prohibits the use of S100A4 as a tumor marker in plasma and serum. PMID: 15192310 |
Ref: Aminothiol WR1065 induces differential gene expression in the presence of wild-type p53. PMID: 15750621 Ref: Overexpression of S100A4 is closely associated with progression of colorectal cancer. PMID: 16097057 |
Ref: Metastasis-associated protein S100A4--a potential prognostic marker for colorectal cancer. PMID: 16615153 Ref: The metastasis-associated gene S100A4 is a novel target of beta-catenin/T-cell factor signaling in colon cancer. PMID: 17101323 |
Ref: Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. PMID: 19417139 Ref: Enhanced S100A4 protein expression is clinicopathologically significant to metastatic potential and p53 dysfunction in colorectal cancer. PMID: 19513503 Ref: [Production and identification of monoclonal antibody against human S100A4.]. PMID: 19961801 Ref: Wnt up your mind - intervention strategies for S100A4-induced metastasis in colon cancer. PMID: 20093727 |
Ref: Expression status of S100A14 and S100A4 correlates with metastatic potential and clinical outcome in colorectal cancer after surgery. PMID: 19956863 Ref: Growth and invasion of sporadic colorectal adenocarcinomas in terms of genetic change. PMID: 20191032 Ref: Overexpression of S100A4 in human cancer cell lines resistant to methotrexate. PMID: 20515499 Ref: Expression of protein S100A4 is a predictor of recurrence in colorectal cancer. PMID: 20712050 Ref: Nuclear S100A4 is a novel prognostic marker in colorectal cancer. PMID: 20719498 |
Ref: Coexpression and nuclear colocalization of metastasis-promoting protein S100A4 and p53 without mutual regulation in colorectal carcinoma. PMID: 20191297 Ref: S100A4 over-expression underlies lymph node metastasis and poor prognosis in colorectal cancer. PMID: 21218086 Ref: Src kinase pathway is involved in NFAT5-mediated S100A4 induction by hyperosmotic stress in colon cancer cells. PMID: 21289293 Ref: Diagnostic and prognostic value of metastasis inducer S100A4 transcripts in plasma of colon, rectal, and gastric cancer patients. PMID: 21354054 Ref: Intervening in beta-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis. PMID: 21403839 Ref: Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer. PMID: 21685359 Ref: Two functional S100A4 monomers are necessary for regulating nonmuscle myosin-IIA and HCT116 cell invasion. PMID: 21721535 Ref: S100A4-induced cell motility and metastasis is restricted by the Wnt/beta-catenin pathway inhibitor calcimycin in colon cancer cells. PMID: 21795396 |
Ref: Prognostic significance of S100A4 mRNA and protein expression in colorectal cancer. PMID: 21837681 Ref: Stat6 activity-related Th2 cytokine profile and tumor growth advantage of human colorectal cancer cells in vitro and in vivo. PMID: 22108090 Ref: Downregulation of S100A4 expression by RNA interference suppresses cell growth and invasion in human colorectal cancer cells. PMID: 22200787 Ref: EMMPRIN is associated with S100A4 and predicts patient outcome in colorectal cancer. PMID: 22782346 Ref: Systemic shRNA mediated knock down of S100A4 in colorectal cancer xenografted mice reduces metastasis formation. PMID: 22878175 Ref: Circulating MACC1 transcripts in colorectal cancer patient plasma predict metastasis and prognosis. PMID: 23166620 |
Ref: Combined aberrant expression of E-cadherin and S100A4, but not beta-catenin is associated with disease-free survival and overall survival in colorectal cancer patients. PMID: 23783026 Ref: Podoplanin, alpha-smooth muscle actin or S100A4 expressing cancer-associated fibroblasts are associated with different prognosis in colorectal cancers. PMID: 24015033 Ref: Clinicopathological and prognostic significance of S100A4 overexpression in colorectal cancer: a meta-analysis. PMID: 24188373 |
Ref: Activation of the PI3K/Akt/mTOR/p70S6K pathway is involved in S100A4-induced viability and migration in colorectal cancer cells. PMID: 24936148 Ref: RAGE mediates S100A4-induced cell motility via MAPK/ERK and hypoxia signaling and is a prognostic biomarker for human colorectal cancer metastasis. PMID: 24952599 Ref: NFAT5-mediated expression of S100A4 contributes to proliferation and migration of renal carcinoma cells. PMID: 25152734 Ref: LIM and SH3 protein 1 induces TGFbeta-mediated epithelial-mesenchymal transition in human colorectal cancer by regulating S100A4 expression. PMID: 25252758 |
Ref: A link between inflammation and metastasis: serum amyloid A1 and A3 induce metastasis, and are targets of metastasis-inducing S100A4. PMID: 24469032 Ref: Increased expressions of SATB1 and S100A4 are associated with poor prognosis in human colorectal carcinoma. PMID: 25257341 Ref: Thioredoxin-1 inhibitor, 1-methylpropyl 2-imidazolyl disulfide, inhibits the growth, migration and invasion of colorectal cancer cell lines. PMID: 25483731 Ref: Circulating Metastasis Associated in Colon Cancer 1 transcripts in gastric cancer patient plasma as diagnostic and prognostic biomarker. PMID: 25574109 Ref: Molecular targets and pathways involved in liver metastasis of colorectal cancer. PMID: 26104118 Ref: Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes. PMID: 26349943 Ref: [Primary culture and characteristics of colorectal cancer-associated fibroblasts]. PMID: 26702529 |
Ref: Expression and clinical significance of Wee1 in colorectal cancer. PMID: 27220319 Ref: Prognostic significance of S100A4 expression in stage II and III colorectal cancer: results from a population-based series and a randomized phase III study on adjuvant chemotherapy. PMID: 27273130 Ref: S100A4 in Cancer Metastasis: Wnt Signaling-Driven Interventions for Metastasis Restriction. PMID: 27331819 Ref: The role of S100a4 (Mts1) in Apc- and Smad4-driven tumour onset and progression. PMID: 27750112 |
Ref: Vitamin D receptor expression and associated gene signature in tumour stromal fibroblasts predict clinical outcome in colorectal cancer. PMID: 27053631 Ref: miR-296 inhibits the metastasis and epithelial-mesenchymal transition of colorectal cancer by targeting S100A4. PMID: 28209128 Ref: Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression. PMID: 28423501 Ref: Vascular Invasion and Stromal S100A4 Expression at the Invasive Front of Colorectal Cancer are Novel Determinants and Tumor Prognostic Markers. PMID: 28775774 |
Ref: Interplay between Trx-1 and S100P promotes colorectal cancer cell epithelial-mesenchymal transition by up-regulating S100A4 through AKT activation. PMID: 29383839 Ref: Phase II trial to investigate the safety and efficacy of orally applied niclosamide in patients with metachronous or sychronous metastases of a colorectal cancer progressing after therapy: the NIKOLO trial. PMID: 29544454 Ref: IL-1beta promotes the nuclear translocaiton of S100A4 protein in gastric cancer cells MGC803 and the cell's stem-like properties through PI3K pathway. PMID: 29932233 Ref: Analysis of the expression of cancer-associated fibroblast- and EMT-related proteins in submucosal invasive colorectal cancer. PMID: 30087711 Ref: S100A4 May Be a Good Prognostic Marker and a Therapeutic Target for Colon Cancer. PMID: 30111999 Ref: S100A4 promotes colon inflammation and colitis-associated colon tumorigenesis. PMID: 30221056 |