Primary Site >> Colorectal Cancer
Gene >> RUNX2
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Ref: Epigenetic inactivation of RUNX3 in microsatellite unstable sporadic colon cancers. PMID: 15386381 |
Ref: Ets-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cells. PMID: 16670084 |
Ref: Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands. PMID: 18290715 |
Ref: Regulation of osteopontin and related proteins in rat CC531 colorectal cancer cells. PMID: 20596651 |
Ref: Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-beta-signaling pathway. PMID: 21088106 Ref: Genetic variation in the transforming growth factor-beta signaling pathway and survival after diagnosis with colon and rectal cancer. PMID: 21365634 |
Ref: Runt-related transcription factor 2 in human colon carcinoma: a potent prognostic factor associated with estrogen receptor. PMID: 22396198 Ref: Loss of RASSF1A synergizes with deregulated RUNX2 signaling in tumorigenesis. PMID: 22710434 |
Ref: Clinical significance and association of RUNX3 hypermethylation frequency with colorectal cancer: a meta-analysis. PMID: 25053885 |
Ref: Cystatin D locates in the nucleus at sites of active transcription and modulates gene and protein expression. PMID: 26364852 Ref: Association of the EGF-TM7 receptor CD97 expression with FLT3-ITD in acute myeloid leukemia. PMID: 26462154 Ref: 1-Benzyl-2-methyl-3-indolylmethylene barbituric acid derivatives: Anti-cancer agents that target nucleophosmin 1 (NPM1). PMID: 26602084 |
Ref: CBX4 Suppresses Metastasis via Recruitment of HDAC3 to the Runx2 Promoter in Colorectal Carcinoma. PMID: 27864346 |
Ref: Celecoxib inhibits osteoblast maturation by suppressing the expression of Wnt target genes. PMID: 28007462 Ref: Genetic variants in the TGFbeta-signaling pathway influence expression of miRNAs in colon and rectal normal mucosa and tumor tissue. PMID: 28061442 Ref: miR-539 inhibits human colorectal cancer progression by targeting RUNX2. PMID: 28938522 Ref: Inflammation-driven colon neoplasmatogenesis in uPA-deficient mice is associated with an increased expression of Runx transcriptional regulators. PMID: 29107070 |
Ref: Ca(2+)/nuclear factor of activated T cells signaling is enriched in early-onset rectal tumors devoid of canonical Wnt activation. PMID: 29124284 Ref: Sodium butyrate has anti-proliferative, pro-differentiating, and immunomodulatory effects in osteosarcoma cells and counteracts the TNFalpha-induced low-grade inflammation. PMID: 29363375 Ref: Liquiritigenin inhibits colorectal cancer proliferation, invasion and epithelial to mesenchymal transition by decreasing expression of runt-related transcription factor 2. PMID: 29471888 Ref: Long non-coding RNA PVT1 functions as an oncogene in human colon cancer through miR-30d-5p/RUNX2 axis. PMID: 29552759 Ref: A feedback loop consisting of RUNX2/LncRNA-PVT1/miR-455 is involved in the progression of colorectal cancer. PMID: 29637007 |