Primary Site >> Colorectal Cancer
Gene >> RSPO2
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Ref: A transposon-based genetic screen in mice identifies genes altered in colorectal cancer. PMID: 19251594 |
Ref: FOXQ1 is overexpressed in colorectal cancer and enhances tumorigenicity and tumor growth. PMID: 20145154 |
Ref: Recurrent R-spondin fusions in colon cancer. PMID: 22895193 |
Ref: RSPO2-LGR5 signaling has tumour-suppressive activity in colorectal cancer. PMID: 24476626 Ref: RSPO fusion transcripts in colorectal cancer in Japanese population. PMID: 24847761 Ref: [Changes of expression of miR-155 in colitis-associated colonic carcinogenesis]. PMID: 24989910 |
Ref: Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness. PMID: 25531322 |
Ref: RSPO2 enriches LGR5(+) spheroid colon cancer stem cells and promotes its metastasis by epithelial-mesenchymal transition. PMID: 27158331 |
Ref: RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis. PMID: 27511199 Ref: RSPO2 suppresses colorectal cancer metastasis by counteracting the Wnt5a/Fzd7-driven noncanonical Wnt pathway. PMID: 28600110 Ref: [Expression of regulatory factor R-spondin family in Wnt signaling pathway in colorectal cancer and its clinical significance]. PMID: 28626093 Ref: Molecular genetics and targeted therapy of WNT-related human diseases (Review). PMID: 28731148 Ref: R-spondin 2 promotes proliferation and migration via the Wnt/beta-catenin pathway in human hepatocellular carcinoma. PMID: 28789406 Ref: RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common Wnt pathway mutations. PMID: 29127379 Ref: Investigation of fusion gene expression in HCT116 cells. PMID: 29181107 |