Primary Site >> Liver Cancer
Gene >> RPTOR
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Ref: Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma. PMID: 22160218 |
Ref: Branched chain amino acid suppresses hepatocellular cancer stem cells through the activation of mammalian target of rapamycin. PMID: 24312415 |
Ref: HDAC2 provides a critical support to malignant progression of hepatocellular carcinoma through feedback control of mTORC1 and AKT. PMID: 24448241 Ref: Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. PMID: 24910242 |
Ref: Influence of Rictor and Raptor Expression of mTOR Signaling on Long-Term Outcomes of Patients with Hepatocellular Carcinoma. PMID: 25371154 Ref: Regular exercise decreases liver tumors development in hepatocyte-specific PTEN-deficient mice independently of steatosis. PMID: 25623824 |
Ref: Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade. PMID: 26716908 Ref: Phosphorylation of mTOR Ser2481 is a key target limiting the efficacy of rapalogs for treating hepatocellular carcinoma. PMID: 27329724 |
Ref: A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis. PMID: 28370287 |