Primary Site >> Colorectal Cancer
Gene >> RPS6KA2
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Ref: Profiling of selenomethionine responsive genes in colon cancer by microarray analysis. PMID: 17374985 |
Ref: Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. PMID: 19615971 |
Ref: Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer. PMID: 21035469 Ref: Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment. PMID: 21999454 |
Ref: Novel TOPK inhibitor HI-TOPK-032 effectively suppresses colon cancer growth. PMID: 22523035 |
Ref: Low expression of RSK4 predicts poor prognosis in patients with colorectal cancer. PMID: 25197367 Ref: Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation. PMID: 25379021 |
Ref: BRAF V600E inhibition stimulates AMP-activated protein kinase-mediated autophagy in colorectal cancer cells. PMID: 26750638 Ref: p90 ribosomal S6 kinase: a potential therapeutic target in lung cancer. PMID: 26791782 Ref: Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis. PMID: 27028006 Ref: The ERK1/2 and mTORC1 Signaling Pathways Are Involved in the Muscarinic Acetylcholine Receptor-Mediated Proliferation of SNU-407 Colon Cancer Cells. PMID: 27167250 |
Ref: RSK activation via ERK modulates human colon cancer cells response to PTHrP. PMID: 28385776 |