Primary Site >> Colorectal Cancer
Gene >> RPS6KA1
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Ref: Selenomethionine induces sustained ERK phosphorylation leading to cell-cycle arrest in human colon cancer cells. PMID: 15513932 |
Ref: Carbachol induces p70S6K1 activation through an ERK-dependent but Akt-independent pathway in human colonic epithelial cells. PMID: 19615971 |
Ref: 3-phosphoinositide-dependent protein kinase-1 regulates proliferation and survival of cancer cells with an activated mitogen-activated protein kinase pathway. PMID: 20197379 |
Ref: Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer. PMID: 21035469 Ref: Regulation of M(3) muscarinic receptor expression and function by transmembrane protein 147. PMID: 21056967 Ref: p-HPEA-EDA, a phenolic compound of virgin olive oil, activates AMP-activated protein kinase to inhibit carcinogenesis. PMID: 21216846 |
Ref: ESM-1 regulates cell growth and metastatic process through activation of NF-kappaB in colorectal cancer. PMID: 22735811 Ref: EGFR and PKC are involved in the activation of ERK1/2 and p90 RSK and the subsequent proliferation of SNU-407 colon cancer cells by muscarinic acetylcholine receptors. PMID: 22865467 Ref: Epidermal growth factor (EGF) regulates alpha5beta1 integrin activation state in human cancer cell lines through the p90RSK-dependent phosphorylation of filamin A. PMID: 23007402 |
Ref: Effect of genomic instability and mutations on the signaling pathways in colon cancer cells. PMID: 23277013 Ref: Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation. PMID: 23580570 |
Ref: G-CSF and G-CSFR are highly expressed in human gastric and colon cancers and promote carcinoma cell proliferation and migration. PMID: 24448357 Ref: TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: relevance in human colorectal tumors. PMID: 24962791 Ref: Low expression of RSK4 predicts poor prognosis in patients with colorectal cancer. PMID: 25197367 Ref: Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation. PMID: 25379021 |
Ref: Sumoylation of HDAC2 promotes NF-kappaB-dependent gene expression. PMID: 25704882 |
Ref: The ERK1/2 and mTORC1 Signaling Pathways Are Involved in the Muscarinic Acetylcholine Receptor-Mediated Proliferation of SNU-407 Colon Cancer Cells. PMID: 27167250 |
Ref: RSK activation via ERK modulates human colon cancer cells response to PTHrP. PMID: 28385776 |
Ref: AKR1B10 activates diacylglycerol (DAG) second messenger in breast cancer cells. PMID: 29846015 |