Primary Site >> Colorectal Cancer
Gene >> RPS6
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Ref: Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells. PMID: 22406476 |
Ref: mTOR inhibition elicits a dramatic response in PI3K-dependent colon cancers. PMID: 23593290 Ref: Sym004, a novel EGFR antibody mixture, can overcome acquired resistance to cetuximab. PMID: 24204198 |
Ref: Incomplete inhibition of phosphorylation of 4E-BP1 as a mechanism of primary resistance to ATP-competitive mTOR inhibitors. PMID: 23542178 Ref: Phloroglucinol induces apoptosis through the regulation of insulin-like growth factor 1 receptor signaling pathways in human colon cancer HT-29 cells. PMID: 24970012 Ref: Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation. PMID: 25379021 |
Ref: Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer. PMID: 25497009 Ref: Frameshift mutations in mammalian target of rapamycin pathway genes and their regional heterogeneity in sporadic colorectal cancers. PMID: 25776026 |
Ref: Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis. PMID: 27028006 |
Ref: Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses. PMID: 27663511 Ref: Metformin transiently inhibits colorectal cancer cell proliferation as a result of either AMPK activation or increased ROS production. PMID: 29167573 |
Ref: High-intensity eccentric training ameliorates muscle wasting in colon 26 tumor-bearing mice. PMID: 29894511 |