Primary Site >> Biliary tract Cancer

Gene >> ROS1

  • 2013
  • 2014
  • 2015
  • 2016
  • 2017
Ref: Mouse model of intrahepatic cholangiocarcinoma validates FIG-ROS as a potent fusion oncogene and therapeutic target.
PMID: 24154728
Ref: Fibroblast growth factor receptor 2 tyrosine kinase fusions define a unique molecular subtype of cholangiocarcinoma.
PMID: 24122810
Ref: Fibroblast growth factor receptor 2 translocations in intrahepatic cholangiocarcinoma.
PMID: 24837095
Ref: Downregulation of ROS-FIG inhibits cell proliferation, colonyformation, cell cycle progression, migration and invasion, while inducing apoptosis in intrahepatic cholangiocarcinoma cells.
PMID: 24968753
Ref: Screening for the FIG-ROS1 fusion in biliary tract carcinomas by nested PCR.
PMID: 25231053
Ref: Clinical and pathological significance of ROS1 expression in intrahepatic cholangiocarcinoma.
PMID: 26475437
Ref: Molecular Pathogenesis and Targeted Therapies for Intrahepatic Cholangiocarcinoma.
PMID: 26405193
Ref: The landscape of targeted therapies for cholangiocarcinoma: current status and emerging targets.
PMID: 27102149
Ref: Expression levels of ROS1/ALK/c-MET and therapeutic efficacy of cetuximab plus chemotherapy in advanced biliary tract cancer.
PMID: 27136744
Ref: Rare Incidence of ROS1 Rearrangement in Cholangiocarcinoma.
PMID: 27121721