Primary Site >> Colorectal Cancer
Gene >> ROR2
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Ref: Wnt5a secretion stimulated by the extracellular calcium-sensing receptor inhibits defective Wnt signaling in colon cancer cells. PMID: 17463182 Ref: Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: transcriptional mechanism of PTK7 in colorectal cancer and that of SEMA6A in undifferentiated ES cells. PMID: 17671748 |
Ref: Importance of Wnt signaling in the tumor stroma microenvironment. PMID: 18781892 |
Ref: Integrative genomic analyses of WNT11: transcriptional mechanisms based on canonical WNT signals and GATA transcription factors signaling. PMID: 19578797 |
Ref: Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer. PMID: 20591152 |
Ref: Extracellular Calcium-Sensing Receptor Inhibition of Intestinal EpithelialTNF Signaling Requires CaSR-Mediated Wnt5a/Ror2 Interaction. PMID: 21603229 Ref: A switch from canonical to noncanonical Wnt signaling mediates drug resistance in colon cancer cells. PMID: 22073312 |
Ref: Extracellular calcium-sensing receptor/PTH knockout mice colons have increased Wnt/beta-catenin signaling, reduced non-canonical Wnt signaling, and increased susceptibility to azoxymethane-induced aberrant crypt foci. PMID: 23545937 |
Ref: High expression of ROR2 in cancer cell correlates with unfavorable prognosis in colorectal cancer. PMID: 25301559 |
Ref: Ror2 as a therapeutic target in cancer. PMID: 25614331 Ref: Insight into the role of Wnt5a-induced signaling in normal and cancer cells. PMID: 25619716 |
Ref: Effect of 1,25-dihydroxyvitamin D3 on the Wnt pathway in non-malignant colonic cells. PMID: 25777538 Ref: ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration. PMID: 27440078 |
Ref: Validation of specificity of antibodies for immunohistochemistry: the case of ROR2. PMID: 27631337 Ref: Molecular genetics and targeted therapy of WNT-related human diseases (Review). PMID: 28731148 |
Ref: ROR1 and ROR2 play distinct and opposing roles in endometrial cancer. PMID: 29395309 Ref: beta-catenin-independent regulation of Wnt target genes by RoR2 and ATF2/ATF4 in colon cancer cells. PMID: 29453334 |