Primary Site >> Liver Cancer

Gene >> ROCK2

  • 2009
  • 2012
  • 2013
  • 2014
  • 2015
  • 2016
  • 2018
Ref: Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion.
PMID: 19205033
 Ref: The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2.
PMID: 21672940
Ref: Rock2 regulates Cdc25A through ubiquitin proteasome system in hepatocellular carcinoma cells.
PMID: 22705122
 Ref: BTB/POZ domain-containing protein 7: epithelial-mesenchymal transition promoter and prognostic biomarker of hepatocellular carcinoma.
PMID: 23325674
 Ref: Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation.
PMID: 25251472
Ref: [Suppression of hepatocellular carcinoma invasion and metastasis by Rho-kinase inhibitor Fasudil through inhibition of BTBD7-ROCK2 signaling pathway].
PMID: 25544168
 Ref: Systemic delivery of microRNA-101 potently inhibits hepatocellular carcinoma in vivo by repressing multiple targets.
PMID: 25693145
Ref: ROCK2 promotes HCC proliferation by CEBPD inhibition through phospho-GSK3beta/beta-catenin signaling.
PMID: 25771860
Ref: MiR-200b/200c/429 subfamily negatively regulates Rho/ROCK signaling pathway to suppress hepatocellular carcinoma metastasis.
PMID: 25909223
Ref: Low Expression of miR-448 Induces EMT and Promotes Invasion by Regulating ROCK2 in Hepatocellular Carcinoma.
PMID: 25969175
Ref: Phosphorylation of nucleophosmin at threonine 234/237 is associated with HCC metastasis.
PMID: 26536659
 Ref: DLC-1 is an independent prognostic marker and potential therapeutic target in hepatocellular cancer.
PMID: 26846339
Ref: RhoE/ROCK2 regulates chemoresistance through NF-kappaB/IL-6/ STAT3 signaling in hepatocellular carcinoma.
PMID: 27213590
Ref: Aptamer-functionalized peptide H3CR5C as a novel nanovehicle for codelivery of fasudil and miRNA-195 targeting hepatocellular carcinoma.
PMID: 27574422
 Ref: In Vivo Phosphoproteome Analysis Reveals Kinome Reprogramming in Hepatocellular Carcinoma.
PMID: 29472430
Ref: The interaction of Lin28A/Rho associated coiled-coil containing protein kinase2 accelerates the malignancy of ovarian cancer.
PMID: 30266988