Primary Site >> Pancreatic Cancer
Gene >> ROCK1
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Ref: Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation. PMID: 22074495 |
Ref: Interplay between beta1-integrin and Rho signaling regulates differential scattering and motility of pancreatic cancer cells by snail and Slug proteins. PMID: 22232555 |
Ref: Hippo pathway elements Co-localize with Occludin: A possible sensor system in pancreatic epithelial cells. PMID: 26451343 Ref: Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer. PMID: 26530532 |
Ref: Ceramide 1-phosphate regulates cell migration and invasion of human pancreatic cancer cells. PMID: 26707801 Ref: Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia. PMID: 27364947 Ref: ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells. PMID: 27824338 |
Ref: ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth. PMID: 28031255 Ref: Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer. PMID: 28841710 Ref: Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy. PMID: 28972449 |
Ref: HIF-3alpha Promotes Metastatic Phenotypes in Pancreatic Cancer by Transcriptional Regulation of the RhoC-ROCK1 Signaling Pathway. PMID: 28928287 Ref: MicroRNA-216b reduces growth, migration and invasion of pancreatic ductal adenocarcinoma cells by directly targeting rho-associated coiled-coil containing protein kinase 1. PMID: 29616134 Ref: Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth. PMID: 29669760 |