Primary Site >> Liver Cancer

Gene >> ROCK1

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Ref: Crude extracts of Euchresta formosana radix inhibit invasion and migration of human hepatocellular carcinoma cells.
PMID: 17695528
Ref: Rho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion.
PMID: 19205033
Ref: Suppression of liver tumor growth and metastasis by adiponectin in nude mice through inhibition of tumor angiogenesis and downregulation of Rho kinase/IFN-inducible protein 10/matrix metalloproteinase 9 signaling.
PMID: 20103676
Ref: Suppression by heat shock protein 20 of hepatocellular carcinoma cell proliferation via inhibition of the mitogen-activated protein kinases and AKT pathways.
PMID: 21769911
Ref: Butein inhibits the migration and invasion of SK-HEP-1 human hepatocarcinoma cells through suppressing the ERK, JNK, p38, and uPA signaling multiple pathways.
PMID: 21770460
Ref: GEF-H1 over-expression in hepatocellular carcinoma promotes cell motility via activation of RhoA signalling.
PMID: 22847784
Ref: ROCK is involved in vasculogenic mimicry formation in hepatocellular carcinoma cell line.
PMID: 25238232
Ref: MiR-335 acts as a potential tumor suppressor miRNA via downregulating ROCK1 expression in hepatocellular carcinoma.
PMID: 25804796
Ref: MiR-506 suppresses cell proliferation and tumor growth by targeting Rho-associated protein kinase 1 in hepatocellular carcinoma.
PMID: 26474697
Ref: MiR-145 suppresses cell proliferation and motility by inhibiting ROCK1 in hepatocellular carcinoma.
PMID: 26615424
Ref: RhoE/ROCK2 regulates chemoresistance through NF-kappaB/IL-6/ STAT3 signaling in hepatocellular carcinoma.
PMID: 27213590
Ref: MiR-199a/b-5p inhibits hepatocellular carcinoma progression by post-transcriptionally suppressing ROCK1.
PMID: 28978024
Ref: Inhibition of MALAT1 sensitizes liver cancer cells to 5-flurouracil by regulating apoptosis through IKKalpha/NF-kappaB pathway.
PMID: 29702091
Ref: The tumor suppressor DLC1 inhibits cancer progression and oncogenic autophagy in hepatocellular carcinoma.
PMID: 29785050
Ref: [Biejiajian Pills inhibits hepatoma carcinoma cell vasculogenic mimicry by suppressing RhoA/ROCK signaling pathway].
PMID: 30187871
Ref: Rho kinase/AMPK axis regulates hepatic lipogenesis during overnutrition.
PMID: 30226474
Ref: The interaction of Lin28A/Rho associated coiled-coil containing protein kinase2 accelerates the malignancy of ovarian cancer.
PMID: 30266988
Ref: Long non-coding RNA linc-ITGB1 promotes cell proliferation, migration, and invasion in human hepatoma carcinoma by up-regulating ROCK1.
PMID: 30279202