Primary Site >> Colorectal Cancer

Gene >> RNF40

  • 2012
  • 2016
  • 2018
Ref: The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination.
PMID: 22021426
Ref: RNF20 Links Histone H2B Ubiquitylation with Inflammation and Inflammation-Associated Cancer.
PMID: 26854224
Ref: Loss of RNF40 decreases NF-kappaB activity in colorectal cancer cells and reduces colitis burden in mice.
PMID: 30321325