Primary Site >> Liver Cancer
Gene >> RIPK3
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Ref: Truncated RIP3 (tRIP3) acts upstream of FADD to induce apoptosis in the human hepatocellular carcinoma cell line QGY-7703. PMID: 16844082 |
Ref: TRAIL induces necroptosis involving RIPK1/RIPK3-dependent PARP-1 activation. PMID: 22814620 |
Ref: RIP3 inhibits inflammatory hepatocarcinogenesis but promotes cholestasis by controlling caspase-8- and JNK-dependent compensatory cell proliferation. PMID: 23972991 |
Ref: IkappaB kinasealpha/beta control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell-death mediator receptor-interacting protein kinase 1. PMID: 27396433 Ref: Questions and controversies: the role of necroptosis in liver disease. PMID: 27924226 |