Primary Site >> Colorectal Cancer
Gene >> RIPK3
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Ref: Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death. PMID: 25675296 Ref: Cobalt chloride induces necroptosis in human colon cancer HT-29 cells. PMID: 25824798 Ref: PolyI:C-Induced, TLR3/RIP3-Dependent Necroptosis Backs Up Immune Effector-Mediated Tumor Elimination In Vivo. PMID: 25898986 Ref: Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis. PMID: 25906152 Ref: A study of thermal dose-induced autophagy, apoptosis and necroptosis in colon cancer cells. PMID: 25974074 Ref: Receptor-interacting protein kinase 3 is a predictor of survival and plays a tumor suppressive role in colorectal cancer. PMID: 25997957 Ref: Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice. PMID: 26693068 |
Ref: Key roles of necroptotic factors in promoting tumor growth. PMID: 26959742 Ref: Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells. PMID: 27098859 Ref: Critical function of the necroptosis adaptor RIPK3 in protecting from intestinal tumorigenesis. PMID: 27344176 Ref: Molecular features of the cytotoxicity of an NHE inhibitor: Evidence of mitochondrial alterations, ROS overproduction and DNA damage. PMID: 27816051 |
Ref: TNF Signaling through RIP1 Kinase Enhances SN38-Induced Death in Colon Adenocarcinoma. PMID: 28087739 Ref: Killing colon cancer cells through PCD pathways by a novel hyaluronic acid-modified shell-core nanoparticle loaded with RIP3 in combination with chloroquine. PMID: 28199887 Ref: Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells. PMID: 28414098 Ref: Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice. PMID: 28476895 Ref: Silymarin induces a multi-targeted cell death process in the human colon cancer cell line HT-29. PMID: 28810529 |
Ref: Cationic liposome co-encapsulation of SMAC mimetic and zVAD using a novel lipid bilayer fusion loaded with MLKL-pDNA for tumour inhibition in vivo. PMID: 28649853 Ref: Antitumor activity of HPA3P through RIPK3-dependent regulated necrotic cell death in colon cancer. PMID: 29487701 Ref: Cationic peroxidase from proso millet induces human colon cancer cell necroptosis by regulating autocrine TNF-alpha and RIPK3 demethylation. PMID: 29528059 Ref: A RIPK3-PGE2 Circuit Mediates Myeloid-Derived Suppressor Cell-Potentiated Colorectal Carcinogenesis. PMID: 30012671 Ref: Resibufogenin suppresses colorectal cancer growth and metastasis through RIP3-mediated necroptosis. PMID: 30029665 |