Primary Site >> Colorectal Cancer
Gene >> RIPK1
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Ref: NF-kappaB activation by the chemopreventive dithiolethione oltipraz is exerted through stimulation of MEKK3 signaling. PMID: 15047705 |
Ref: TRAIL induces receptor-interacting protein 1-dependent and caspase-dependent necrosis-like cell death under acidic extracellular conditions. PMID: 17210702 |
Ref: Prostaglandin synthase 2/cyclooxygenase 2 (PTGS2/COX2) 8473T>C polymorphism associated with prognosis for patients with colorectal cancer treated with capecitabine and oxaliplatin. PMID: 19219602 Ref: Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines. PMID: 19352384 |
Ref: HSP70 interacts with TRAF2 and differentially regulates TNFalpha signalling in human colon cancer cells. PMID: 19243468 Ref: Expression of CARD6, an NF-kappaB activator, in gastric, colorectal and oesophageal cancers. PMID: 20025480 Ref: Combination of ionising irradiation and hyperthermia activates programmed apoptotic and necrotic cell death pathways in human colorectal carcinoma cells. PMID: 21069267 |
Ref: RIPK1 and CASP7 polymorphism as prognostic markers for survival in patients with colorectal cancer after complete resection. PMID: 20567846 Ref: Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment. PMID: 21372226 Ref: Caspase-2 is required for DNA damage-induced expression of the CDK inhibitor p21(WAF1/CIP1). PMID: 21475302 |
Ref: Role of miR-19b and its target mRNAs in 5-fluorouracil resistance in colon cancer cells. PMID: 22382630 |
Ref: Resistance to hypoxia-induced necroptosis is conferred by glycolytic pyruvate scavenging of mitochondrial superoxide in colorectal cancer cells. PMID: 23640464 Ref: Inhibition of GSK3B bypass drug resistance of p53-null colon carcinomas by enabling necroptosis in response to chemotherapy. PMID: 23729362 |
Ref: Gene Expression Profiling Identifies Important Genes Affected by R2 Compound Disrupting FAK and P53 Complex. PMID: 24452144 Ref: The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells. PMID: 24577083 Ref: Effects of silencing RIP1 with siRNA on the biological behavior of the LoVo human colon cancer cell line. PMID: 24932290 Ref: GSK3A is redundant with GSK3B in modulating drug resistance and chemotherapy-induced necroptosis. PMID: 24984063 Ref: AngioMatrix, a signature of the tumor angiogenic switch-specific matrisome, correlates with poor prognosis for glioma and colorectal cancer patients. PMID: 25301723 |
Ref: Genomic instability causes HGF gene activation in colon cancer cells, promoting their resistance to necroptosis. PMID: 25244939 Ref: Spatial organization of the tenascin-C microenvironment in experimental and human cancer. PMID: 25611571 Ref: Differential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death. PMID: 25675296 Ref: Adenosine induces apoptosis through TNFR1/RIPK1/P38 axis in colon cancer cells. PMID: 25817730 Ref: Cobalt chloride induces necroptosis in human colon cancer HT-29 cells. PMID: 25824798 Ref: Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis. PMID: 25906152 Ref: Down-Regulating Receptor Interacting Protein Kinase 1 (RIP1) Promotes Oxaliplatin-Induced Tca8113 Cell Apoptosis. PMID: 26460489 Ref: Necrostatin-1 reduces intestinal inflammation and colitis-associated tumorigenesis in mice. PMID: 26693068 |
Ref: A critical role for cellular inhibitor of protein 2 (cIAP2) in colitis-associated colorectal cancer and intestinal homeostasis mediated by the inflammasome and survival pathways. PMID: 26037070 Ref: Inhibition of caspases primes colon cancer cells for 5-fluorouracil-induced TNF-alpha-dependent necroptosis driven by RIP1 kinase and NF-kappaB. PMID: 26522725 Ref: Cooperative TRAIL production mediates IFNalpha/Smac mimetic-induced cell death in TNFalpha-resistant solid cancer cells. PMID: 26788912 Ref: Inhibition of colon cancer growth by docosahexaenoic acid involves autocrine production of TNFalpha. PMID: 26853468 Ref: Key roles of necroptotic factors in promoting tumor growth. PMID: 26959742 Ref: N-end rule pathway inhibition assists colon tumor regression via necroptosis. PMID: 27556106 Ref: Bifidobacteria Prevent Tunicamycin-Induced Endoplasmic Reticulum Stress and Subsequent Barrier Disruption in Human Intestinal Epithelial Caco-2 Monolayers. PMID: 27611782 |
Ref: MUC13 protects colorectal cancer cells from death by activating the NF-kappaB pathway and is a potential therapeutic target. PMID: 27399336 Ref: TNF Signaling through RIP1 Kinase Enhances SN38-Induced Death in Colon Adenocarcinoma. PMID: 28087739 Ref: Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells. PMID: 28414098 Ref: Silymarin induces a multi-targeted cell death process in the human colon cancer cell line HT-29. PMID: 28810529 Ref: Alkynyl gold(I) complex triggers necroptosis via ROS generation in colorectal carcinoma cells. PMID: 28892675 Ref: Bromoethylindole (BEI-9) redirects NF-kappaB signaling induced by camptothecin and TNFalpha to promote cell death in colon cancer cells. PMID: 29116428 |
Ref: Cationic peroxidase from proso millet induces human colon cancer cell necroptosis by regulating autocrine TNF-alpha and RIPK3 demethylation. PMID: 29528059 Ref: RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca(2+) Uptake and Promotes Colorectal Oncogenesis. PMID: 29531160 Ref: The response to neoadjuvant chemoradiotherapy with 5-fluorouracil in locally advanced rectal cancer patients: a predictive proteomic signature. PMID: 29681787 Ref: Hsa_circ_0071589 promotes carcinogenesis via the miR-600/EZH2 axis in colorectal cancer. PMID: 29710537 Ref: Annonaceous acetogenin mimic AA005 suppresses human colon cancer cell growth in vivo through downregulation of Mcl-1. PMID: 29921883 Ref: Upregulated miR-1258 regulates cell cycle and inhibits cell proliferation by directly targeting E2F8 in CRC. PMID: 30144184 |