Primary Site >> Colorectal Cancer

Gene >> RICTOR

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Ref: Curcumin inhibits proliferation of colorectal carcinoma by modulating Akt/mTOR signaling.
PMID: 19661333
Ref: Targeted inhibition of mammalian target of rapamycin signaling inhibits tumorigenesis of colorectal cancer.
PMID: 19934294
Ref: Targeting mTORC2 inhibits colon cancer cell proliferation in vitro and tumor formation in vivo.
PMID: 20226010
Ref: mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways.
PMID: 21430067
Ref: Rictor regulates FBXW7-dependent c-Myc and cyclin E degradation in colorectal cancer cells.
PMID: 22285861
Ref: Downregulation of miR-144 is associated with colorectal cancer progression via activation of mTOR signaling pathway.
PMID: 22983984
Ref: MiR-424/503-mediated Rictor upregulation promotes tumor progression.
PMID: 24244675
Ref: The preclinical evaluation of the dual mTORC1/2 inhibitor INK-128 as a potential anti-colorectal cancer agent.
PMID: 25692620
Ref: Autophagy-related genes Raptor, Rictor, and Beclin1 expression and relationship with multidrug resistance in colorectal carcinoma.
PMID: 26363527
Ref: Mechanism of Chemoprevention against Colon Cancer Cells Using Combined Gelam Honey and Ginger Extract via mTOR and Wnt/beta-catenin Pathways.
PMID: 26434873
Ref: [Expression of Rictor and mTOR in colorectal cancer and their clinical significance].
PMID: 27063170
Ref: mTOR activity and its prognostic significance in human colorectal carcinoma depending on C1 and C2 complex-related protein expression.
PMID: 27729429
Ref: Overexpression of Rictor protein in colorectal cancer is correlated with tumor progression and prognosis.
PMID: 29113267
Ref: Uncoupling TORC2 from AGC kinases inhibits tumour growth.
PMID: 29156676
Ref: The Effects of Different mTOR Inhibitors in EGFR Inhibitor Resistant Colon Carcinoma Cells.
PMID: 29882195