Primary Site >> Colorectal Cancer

Gene >> RHOC

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Ref: Conditional ROCK activation in vivo induces tumor cell dissemination and angiogenesis.
PMID: 15604264
 Ref: PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility.
PMID: 16540666
Ref: Reciprocal regulation of RhoA and RhoC characterizes the EMT and identifies RhoC as a prognostic marker of colon carcinoma.
PMID: 16715134
 Ref: Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells.
PMID: 18172863
 Ref: Inhibitory effects of adenovirus mediated tandem expression of RhoA and RhoC shRNAs in HCT116 cells.
PMID: 19374769
Ref: Expression of RhoA and RhoC in colorectal carcinoma and its relations with clinicopathological parameters.
PMID: 19499974
 Ref: Silencing of RhoA and RhoC expression by RNA interference suppresses human colorectal carcinoma growth in vivo.
PMID: 20828398
 Ref: Clinical significance of Rho GDP dissociation inhibitor 2 in colorectal carcinoma.
PMID: 21698524
Ref: Hepatic tumors: region-of-interest versus volumetric analysis for quantification of attenuation at CT.
PMID: 22357887
 Ref: Src-mediated phosphorylation of the tyrosine phosphatase PRL-3 is required for PRL-3 promotion of Rho activation, motility and invasion.
PMID: 23691193
 Ref: MicroRNA-10b is upregulated and has an invasive role in colorectal cancer through enhanced Rhoc expression.
PMID: 25606801
 Ref: miR-10b promotes invasion by targeting HOXD10 in colorectal cancer.
PMID: 27347170
 Ref: Scorpion Venom Causes Upregulation of p53 and Downregulation of Bcl-xL and BID Protein Expression by Modulating Signaling Proteins Erk(1/2) and STAT3, and DNA Damage in Breast and Colorectal Cancer Cell Lines.
PMID: 28438053
Ref: The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells.
PMID: 29772566
Ref: Formin-like 3 regulates RhoC/FAK pathway and actin assembly to promote cell invasion in colorectal carcinoma.
PMID: 30228782