Primary Site >> Colorectal Cancer

Gene >> RHOB

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Ref: Mechanism of lovastatin-induced apoptosis in intestinal epithelial cells.
PMID: 11895868
 Ref: Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion.
PMID: 14630701
Ref: Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes.
PMID: 15520171
 Ref: New drugs in cancer therapy, National Tumor Institute, Naples, 17-18 June 2004.
PMID: 15655420
Ref: Global gene expression profiling of cells overexpressing SMC3.
PMID: 16156898
 Ref: Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells.
PMID: 18172863
 Ref: Analysis of differential gene expression in colorectal cancer and stroma using fluorescence-activated cell sorting purification.
PMID: 19401702
 Ref: JNK-mediated transcriptional upregulation of RhoB is critical for apoptosis of HCT-116 colon cancer cells by a novel diarylsulfonylurea derivative.
PMID: 20683666
 Ref: miR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells.
PMID: 21872591
 Ref: Clinical significance of Rho GDP dissociation inhibitor 2 in colorectal carcinoma.
PMID: 21698524
Ref: Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reduced DNA binding activity of NF-kappaB.
PMID: 22227305
Ref: Insidious role of nitric oxide in migration/invasion of colon cancer cells by upregulating MMP-2/9 via activation of cGMP-PKG-ERK signaling pathways.
PMID: 22419013
 Ref: CCL24 contributes to HCC malignancy via RhoB- VEGFA-VEGFR2 angiogenesis pathway and indicates poor prognosis.
PMID: 28042950
Ref: The p53 isoform delta133p53ss regulates cancer cell apoptosis in a RhoB-dependent manner.
PMID: 28212429
 Ref: miR-223-RhoB signaling pathway regulates the proliferation and apoptosis of colon adenocarcinoma.
PMID: 29660302
Ref: The Epigenetic Factor KDM2B Regulates EMT and Small GTPases in Colon Tumor Cells.
PMID: 29772566