Primary Site >> Colorectal Cancer
Gene >> RFC1
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Ref: Immunological and patho-clinical observations of a patient with rectal carcinoma after long term administration of thymic extract (TFX). PMID: 995756 |
Ref: ZD1694 (Tomudex): a new thymidylate synthase inhibitor with activity in colorectal cancer. PMID: 7577036 Ref: Folate-based thymidylate synthase inhibitors as anticancer drugs. PMID: 8624289 |
Ref: Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients. PMID: 14676127 |
Ref: Low expression of reduced folate carrier-1 and folylpolyglutamate synthase correlates with lack of a deleted in colorectal carcinoma mRNA splice variant in normal-appearing mucosa of colorectal carcinoma patients. PMID: 16122883 |
Ref: Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. PMID: 16963246 Ref: Colorectal carcinomas with microsatellite instability display increased thymidylate synthase gene expression levels. PMID: 18039426 |
Ref: Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations. PMID: 18842806 Ref: The reduced folate carrier (RFC1) 80G > A and folate hydrolase 1 (FOLH1) 1561C > T polymorphisms and the risk of colorectal cancer: a nested case-referent study. PMID: 19172696 |
Ref: Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer. PMID: 18926688 Ref: Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom1R Apc Min/+ mice. PMID: 19194513 Ref: Synthetic lethal genetic interactions that decrease somatic cell proliferation in Caenorhabditis elegans identify the alternative RFC CTF18 as a candidate cancer drug target. PMID: 19846659 |
Ref: Mutational and expressional analysis of RFC3, a clamp loader in DNA replication, in gastric and colorectal cancers. PMID: 20573375 |
Ref: Association of MTHFR, MTR, MTRR, RFC1, and DHFR gene polymorphisms with susceptibility to sporadic colon cancer. PMID: 21438757 |
Ref: Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolism. PMID: 24500500 |
Ref: DNA methylation and expression of the folate transporter genes in colorectal cancer. PMID: 25697897 Ref: Expression of Folate Pathway Genes in Stage III Colorectal Cancer Correlates with Recurrence Status Following Adjuvant Bolus 5-FU-Based Chemotherapy. PMID: 26193446 |
Ref: Contributions to the phytotherapies of digestive disorders: Traditional knowledge and cultural drivers of Manoor Valley, Northern Pakistan. PMID: 27353866 |
Ref: Relationship between folate concentration and expression of folate-associated genes in tissue and plasma after intraoperative administration of leucovorin in patients with colorectal cancer. PMID: 30269276 |