Primary Site >> Pancreatic Cancer

Gene >> REG4

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Ref: Molecular cloning, expression and chromosomal localization of a novel human REG family gene, REG III.
PMID: 15556304
Ref: Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma.
PMID: 16086444
Ref: [Pancreatic tumors].
PMID: 19434873
Ref: Serum REG4 level is a predictive biomarker for the response to preoperative chemoradiotherapy in patients with pancreatic cancer.
PMID: 19546835
Ref: The reg4 gene, amplified in the early stages of pancreatic cancer development, is a promising therapeutic target.
PMID: 19834624
Ref: Serum tumor antigen REG4 as a diagnostic biomarker in pancreatic ductal adenocarcinoma.
PMID: 19789838
Ref: REG4 contributes to the invasiveness of pancreatic cancer by upregulating MMP-7 and MMP-9.
PMID: 22957785
Ref: Discovery of novel candidate oncogenes in pancreatic carcinoma using high-throughput microarrays.
PMID: 24719914
Ref: The pancreatic cancer secreted REG4 promotes macrophage polarization to M2 through EGFR/AKT/CREB pathway.
PMID: 26531138
Ref: Prognostic and diagnostic value of REG4 serum and tissue expression in pancreatic ductal adenocarcinoma.
PMID: 29542402