Primary Site >> Colorectal Cancer

Gene >> REG1A

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Ref: Colon-cancer cell variants producing regressive tumors in syngeneic rats, unlike variants yielding progressive tumors, attach to interstitial collagens through integrin alpha2beta1.
PMID: 8631595
Ref: Ectopic expression of reg protein: A marker of colorectal mucosa at risk for neoplasia.
PMID: 9834348
Ref: A robust method for isotopic riboprobe in situ hybridisation to localise mRNAs in routine pathology specimens.
PMID: 9728289
Ref: pap, reg Ialpha and reg Ibeta mRNAs are concomitantly up-regulated during human colorectal carcinogenesis.
PMID: 10328217
Ref: Expression of REG protein during cell growth and differentiation of two human colon carcinoma cell lines.
PMID: 10375374
Ref: Death from early colorectal cancer is predicted by the presence of transcripts of the REG gene family.
PMID: 10901369
Ref: Upregulation of Reg 1alpha and GW112 in the epithelium of inflamed colonic mucosa.
PMID: 11302958
Ref: Reg gene family and human diseases.
PMID: 14669303
Ref: The role of gastrin in colorectal carcinogenesis.
PMID: 15570843
Ref: Possible role of REG Ialpha protein in ulcerative colitis and colitic cancer.
PMID: 15914572
Ref: Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas.
PMID: 16401477
Ref: Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes.
PMID: 17106246
Ref: Expression profiling of fecal colonocytes for RNA-based screening of colorectal cancer.
PMID: 17912428
Ref: REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis.
PMID: 18452172
Ref: Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis.
PMID: 19900450
Ref: Involvement of the IL-22/REG Ialpha axis in ulcerative colitis.
PMID: 20065946
Ref: REG IV overexpression in an early stage of colorectal carcinogenesis: an immunohistochemical study.
PMID: 20183800
Ref: Expression profile of the REG gene family in colorectal carcinoma.
PMID: 21339177
Ref: Relationship between RegIV gene expression to outcomes in colorectal cancer.
PMID: 21381041
Ref: Microsatellite instability status affects gene expression profiles in early onset colorectal cancer patients.
PMID: 23992855
Ref: Inducible intestine-specific deletion of Kruppel-like factor 5 is characterized by a regenerative response in adult mouse colon.
PMID: 24440658
Ref: Bacterially-Associated Transcriptional Remodelling in a Distinct Genomic Subtype of Colorectal Cancer Provides a Plausible Molecular Basis for Disease Development.
PMID: 27846243