Primary Site >> Colorectal Cancer

Gene >> RBPJ

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Ref: Identification and characterization of human HES2, HES3, and HES5 genes in silico.
PMID: 15254753
Ref: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells.
PMID: 16525728
Ref: Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer.
PMID: 17611704
Ref: Gamma-secretase inhibitors enhance taxane-induced mitotic arrest and apoptosis in colon cancer cells.
PMID: 18166351
Ref: Mastermind-like transcriptional co-activators: emerging roles in regulating cross talk among multiple signaling pathways.
PMID: 18758483
Ref: KLF4 gene expression is inhibited by the notch signaling pathway that controls goblet cell differentiation in mouse gastrointestinal tract.
PMID: 19109406
Ref: Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling.
PMID: 21251616
Ref: Overcoming stemness and chemoresistance in colorectal cancer through miR-195-5p-modulated inhibition of notch signaling.
PMID: 29852230