Primary Site >> Biliary tract Cancer

Gene >> RASSF1

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Ref: Frequent loss of chromosome 3p and hypermethylation of RASSF1A in cholangiocarcinoma.
PMID: 12399230
 Ref: Aberrant promoter hypermethylation of multiple genes in gallbladder carcinoma and chronic cholecystitis.
PMID: 15447999
Ref: Promoter hypermethylation of DAP-kinase is associated with poor survival in primary biliary tract carcinoma patients.
PMID: 15471559
 Ref: Promoter methylation profiles of tumor suppressor genes in intrahepatic and extrahepatic cholangiocarcinoma.
PMID: 15467712
Ref: Inactivation of RASSF1A, the tumor suppressor gene at 3p21.3 in extrahepatic cholangiocarcinoma.
PMID: 15761971
Ref: Promoter methylation and loss of coding exons of the fragile histidine triad (FHIT) gene in intrahepatic cholangiocarcinomas.
PMID: 16343073
 Ref: Frequent epigenetic inactivation of chromosome 3p candidate tumor suppressor genes in gallbladder carcinoma.
PMID: 17084965
Ref: Hypermethylation of the Ras association domain family 1A (RASSF1A) gene in gallbladder cancer.
PMID: 18182852
 Ref: CpG island hypermethylation and repetitive DNA hypomethylation in premalignant lesion of extrahepatic cholangiocarcinoma.
PMID: 19763613
 Ref: MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes.
PMID: 20146264
 Ref: miR-373 negatively regulates methyl-CpG-binding domain protein 2 (MBD2) in hilar cholangiocarcinoma.
PMID: 21086164
Ref: Hepatitis C virus core upregulates the methylation status of the RASSF1A promoter through regulation of SMYD3 in hilar cholangiocarcinoma cells.
PMID: 21450690
 Ref: Molecular biology of gallbladder cancer: potential clinical implications.
PMID: 23112962
 Ref: Mutations of candidate tumor suppressor genes at chromosome 3p in intrahepatic cholangiocarcinoma.
PMID: 29122566
Ref: DNA Methylation Markers Improve the Sensitivity of Endoscopic Retrograde Cholangiopancreatography-Based Brushing Cytology in Extrahepatic Cholangiocarcinoma.
PMID: 29484968