Primary Site >> Liver Cancer
Gene >> RAD51
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Ref: Induction of mutations in DNA-repair deficient bacteria by a liver microsomal metabolite of aflatoxin B1. PMID: 4593223 |
Ref: Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells. PMID: 18316552 |
Ref: Genetic inactivation of the Fanconi anemia gene FANCC identified in the hepatocellular carcinoma cell line HuH-7 confers sensitivity towards DNA-interstrand crosslinking agents. PMID: 20509860 Ref: PPARalpha-dependent activation of cell cycle control and DNA repair genes in hepatic nonparenchymal cells. PMID: 20813756 Ref: Deletion of the nuclear isoform of poly(ADP-ribose) glycohydrolase (PARG) reveals its function in DNA repair, genomic stability and tumorigenesis. PMID: 20926829 |
Ref: Mutation of herpesvirus Saimiri ORF51 glycoprotein specifically targets infectivity to hepatocellular carcinoma cell lines. PMID: 21197456 Ref: Lack of association of RAD51 genetic variations with hepatitis B virus clearance and occurrence of hepatocellular carcinoma in a Korean population. PMID: 21915862 |
Ref: Cocarcinogenic effects of intrahepatic bile acid accumulation in cholangiocarcinoma development. PMID: 24255171 Ref: Poly (ADP-ribose) polymerase inhibition synergizes with the NF-kappaB inhibitor DHMEQ to kill hepatocellular carcinoma cells. PMID: 25072752 |
Ref: Rac1 promotes diethylnitrosamine (DEN)-induced formation of liver tumors. PMID: 25556150 Ref: Harmine suppresses homologous recombination repair and inhibits proliferation of hepatoma cells. PMID: 26382920 |
Ref: Gefitinib Synergizes with Irinotecan to Suppress Hepatocellular Carcinoma via Antagonizing Rad51-Mediated DNA-Repair. PMID: 26752698 Ref: beta2-spectrin depletion impairs DNA damage repair. PMID: 27248179 |
Ref: Targeting histone deacetylase 4/ubiquitin-conjugating enzyme 9 impairs DNA repair for radiosensitization of hepatocellular carcinoma cells in mice. PMID: 28646552 Ref: Rad51 Interacts with Non-structural 3 Protein of Hepatitis C Virus and Regulates Viral Production. PMID: 28729862 Ref: Ubiquitin-specific protease 21 stabilizes BRCA2 to control DNA repair and tumor growth. PMID: 28743957 Ref: Caffeine Has a Synergistic Anticancer Effect with Cisplatin via Inhibiting Fanconi Anemia Group D2 Protein Monoubiquitination in Hepatocellular Carcinoma Cells. PMID: 28855448 Ref: Downregulation of DNA repair proteins and increased DNA damage in hypoxic colon cancer cells is a therapeutically exploitable vulnerability. PMID: 29156796 |
Ref: Nonstructural Protein 5A Impairs DNA Damage Repair: Implications for Hepatitis C Virus-Mediated Hepatocarcinogenesis. PMID: 29563287 Ref: Corylin increases the sensitivity of hepatocellular carcinoma cells to chemotherapy through long noncoding RNA RAD51-AS1-mediated inhibition of DNA repair. PMID: 29749376 Ref: The LncRNA H19/miR-193a-3p axis modifies the radio-resistance and chemotherapeutic tolerance of hepatocellular carcinoma cells by targeting PSEN1. PMID: 29968942 Ref: Melatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair. PMID: 30201872 |