Primary Site >> Esophagus Cancer

Gene >> RAC1

  • 2010
  • 2013
  • 2014
  • 2016
  • 2017
  • 2018
Ref: P66shc and its downstream Eps8 and Rac1 proteins are upregulated in esophageal cancers.
PMID: 20565814
Ref: Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.
PMID: 23525077
Ref: Suppressing the formation of lipid raft-associated Rac1/PI3K/Akt signaling complexes by curcumin inhibits SDF-1alpha-induced invasion of human esophageal carcinoma cells.
PMID: 23192861
Ref: F-box protein complex FBXL19 regulates TGFbeta1-induced E-cadherin down-regulation by mediating Rac3 ubiquitination and degradation.
PMID: 24684802
Ref: Regulation of CXCR4/AKT-signaling-induced cell invasion and tumor metastasis by RhoA, Rac-1, and Cdc42 in human esophageal cancer.
PMID: 26631033
Ref: Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma.
PMID: 28031525
Ref: Ropivacaine inhibits the migration of esophageal cancer cells via sodium-channel-independent but prenylation-dependent inhibition of Rac1/JNK/paxillin/FAK.
PMID: 29777701