Primary Site >> Colorectal Cancer

Gene >> PYCARD

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Ref: Translational oncogenomics: toward rational therapeutic decision-making.
PMID: 11880707
Ref: A proapoptotic caspase recruitment domain protein gene, TMS1, is hypermethylated in human breast and gastric cancers.
PMID: 12553049
Ref: Methylation of ASC/TMS1, a proapoptotic gene responsible for activating procaspase-1, in human colorectal cancer.
PMID: 14643031
Ref: Methylation-induced silencing of ASC and the effect of expressed ASC on p53-mediated chemosensitivity in colorectal cancer.
PMID: 16331272
Ref: The methylation status of the TMS1/ASC gene in cholangiocarcinoma and its clinical significance.
PMID: 16911948
Ref: Methylation-induced silencing of ASC/TMS1, a pro-apoptotic gene, is a late-stage event in colorectal cancer.
PMID: 17986858
Ref: Sodium butyrate restores ASC expression and induces apoptosis in LS174T cells.
PMID: 23064206
Ref: Genes with aberrant expression in murine preneoplastic intestine show epigenetic and expression changes in normal mucosa of colon cancer patients.
PMID: 24169962
Ref: Commonality and differences of methylation signatures in the plasma of patients with pancreatic cancer and colorectal cancer.
PMID: 24288256
Ref: Inflammasome-independent NLRP3 is required for epithelial-mesenchymal transition in colon cancer cells.
PMID: 26968633