Primary Site >> Colorectal Cancer
Gene >> PTPRU
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Ref: A randomized clinical trial of combination chemotherapy in advanced colorectal cancer. PMID: 3303905 |
Ref: Anti-tumour effects of an antibody-carboxypeptidase G2 conjugate in combination with phenol mustard prodrugs. PMID: 7577451 Ref: Increased mRNA expression of the receptor-like protein tyrosine phosphatase alpha in late stage colon carcinomas. PMID: 7621435 |
Ref: Histochemically demonstrable protein tyrosine phosphatase in human breast and colorectal cancer: large decrease in its activity in colorectal cancer suggests a tumor suppressor role in colorectal mucosal cells. PMID: 8687156 |
Ref: Elevated expression of the cdc25A protein phosphatase in colon cancer. PMID: 9596996 |
Ref: Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket. PMID: 15611135 |
Ref: Silencing of SH-PTP2 defines a crucial role in the inactivation of epidermal growth factor receptor by 5-aminosalicylic acid in colon cancer cells. PMID: 16082388 Ref: Protein-tyrosine phosphatase PCP-2 inhibits beta-catenin signaling and increases E-cadherin-dependent cell adhesion. PMID: 16574648 Ref: DEP-1 protein tyrosine phosphatase inhibits proliferation and migration of colon carcinoma cells and is upregulated by protective nutrients. PMID: 16682945 |
Ref: Identification of STAT3 as a substrate of receptor protein tyrosine phosphatase T. PMID: 17360477 |
Ref: Phosphatase inhibitor, sodium stibogluconate, in combination with interferon (IFN) alpha 2b: phase I trials to identify pharmacodynamic and clinical effects. PMID: 22201704 |
Ref: Unusually long-term responses to vemurafenib in BRAF V600E mutated colon and thyroid cancers followed by the development of rare RAS activating mutations. PMID: 30036146 |