Primary Site >> Colorectal Cancer
Gene >> PTPRK
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Ref: Identification of target proteins of N-acetylglucosaminyl transferase V in human colon cancer and implications of protein tyrosine phosphatase kappa in enhanced cancer cell migration. PMID: 16404719 |
Ref: A transposon-based genetic screen in mice identifies genes altered in colorectal cancer. PMID: 19251594 |
Ref: Comparative quantitation of aberrant glycoforms by lectin-based glycoprotein enrichment coupled with multiple-reaction monitoring mass spectrometry. PMID: 20462175 |
Ref: Protein tyrosine phosphatase kappa (PTPRK) is a negative regulator of adhesion and invasion of breast cancer cells, and associates with poor prognosis of breast cancer. PMID: 23552869 Ref: Receptor-like protein tyrosine phosphatase kappa negatively regulates the apoptosis of prostate cancer cells via the JNK pathway. PMID: 24002526 |
Ref: RSPO fusion transcripts in colorectal cancer in Japanese population. PMID: 24847761 |
Ref: Receptor-type protein tyrosine phosphatase kappa directly dephosphorylates CD133 and regulates downstream AKT activation. PMID: 24882578 Ref: Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness. PMID: 25531322 |
Ref: Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function. PMID: 26700806 |
Ref: Loss of AXIN1 drives acquired resistance to WNT pathway blockade in colorectal cancer cells carrying RSPO3 fusions. PMID: 28100566 Ref: Investigation of fusion gene expression in HCT116 cells. PMID: 29181107 |