Primary Site >> Colorectal Cancer
Gene >> PTP4A2
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Ref: Structural insights into molecular function of the metastasis-associated phosphatase PRL-3. PMID: 14704153 |
Ref: Generation of PRL-3- and PRL-1-specific monoclonal antibodies as potential diagnostic markers for cancer metastases. PMID: 15788667 Ref: PRL phosphatases as potential molecular targets in cancer. PMID: 16275986 |
Ref: PRL tyrosine phosphatases regulate rho family GTPases to promote invasion and motility. PMID: 16540666 |
Ref: Expression of the human phosphatases of regenerating liver (PRLs) in colonic adenocarcinoma and its correlation with lymph node metastasis. PMID: 17440740 |
Ref: Monoclonal antibodies target intracellular PRL phosphatases to inhibit cancer metastases in mice. PMID: 18364570 |
Ref: Targeted deletion of the metastasis-associated phosphatase Ptp4a3 (PRL-3) suppresses murine colon cancer. PMID: 23555575 Ref: Src-mediated phosphorylation of the tyrosine phosphatase PRL-3 is required for PRL-3 promotion of Rho activation, motility and invasion. PMID: 23691193 |
Ref: MiR-29c mediates epithelial-to-mesenchymal transition in human colorectal carcinoma metastasis via PTP4A and GNA13 regulation of beta-catenin signaling. PMID: 25193986 |