Primary Site >> Colorectal Cancer

Gene >> PTK7

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Ref: Organization of the human PTK7 gene encoding a receptor protein tyrosine kinase-like molecule and alternative splicing of its mRNA.
PMID: 12427550
Ref: The GxxxG-containing transmembrane domain of the CCK4 oncogene does not encode preferential self-interactions.
PMID: 15683231
Ref: Comparative integromics on non-canonical WNT or planar cell polarity signaling molecules: transcriptional mechanism of PTK7 in colorectal cancer and that of SEMA6A in undifferentiated ES cells.
PMID: 17671748
Ref: Silencing of PTK7 in colon cancer cells: caspase-10-dependent apoptosis via mitochondrial pathway.
PMID: 21103379
Ref: The cytosolic domain of protein-tyrosine kinase 7 (PTK7), generated from sequential cleavage by a disintegrin and metalloprotease 17 (ADAM17) and gamma-secretase, enhances cell proliferation and migration in colon cancer cells.
PMID: 22665490
Ref: Detection of cadherin-17 in human colon cancer LIM1215 cell secretome and tumour xenograft-derived interstitial fluid and plasma.
PMID: 23557862
Ref: Protein-tyrosine pseudokinase 7 (PTK7) directs cancer cell motility and metastasis.
PMID: 25006253
Ref: Overexpression of the Promigratory and Prometastatic PTK7 Receptor Is Associated with an Adverse Clinical Outcome in Colorectal Cancer.
PMID: 25962058
Ref: Quantitative Profiling of Protein Tyrosine Kinases in Human Cancer Cell Lines by Multiplexed Parallel Reaction Monitoring Assays.
PMID: 26631510
Ref: PTK7 overexpression in colorectal tumors: Clinicopathological correlation and prognosis relevance.
PMID: 27499181
Ref: PTK7 localization and protein stability is affected by canonical Wnt ligands.
PMID: 28420671
Ref: miR2055p/PTK7 axis is involved in the proliferation, migration and invasion of colorectal cancer cells.
PMID: 29488611