Primary Site >> Colorectal Cancer

Gene >> PTK2B

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Ref: Preferential requirement for protein tyrosine phosphatase activity in the 12-O-tetradecanoylphorbol-13-acetate-induced differentiation of human colon cancer cells.
PMID: 7488237
Ref: Induction of apoptosis in colon cancer cells by nonsteroidal anti-inflammatory drugs.
PMID: 9752793
Ref: [Preparation and characterization of potential antineoplastic agents].
PMID: 10401154
Ref: The in vitro effects of H-89, a specific inhibitor of protein kinase A, in the human colonic carcinoma cell line Caco-2.
PMID: 14639124
Ref: Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility.
PMID: 16368433
Ref: Transcriptional upregulation of gastrin in response to peroxisome proliferator-activated receptor gamma agonist triggers cell survival pathways.
PMID: 18195488
Ref: [Expression of proline-rich tyrosine kinase-2 in human primary colorectal carcinoma and its prognostic implication].
PMID: 18785580
Ref: Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines.
PMID: 19637312
Ref: Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: effect of a chemo-protective diet.
PMID: 21406606
Ref: [Influence of Pyk2 on hepatic metastasis and ultrastructure of human colonic cancer cells].
PMID: 21503113
Ref: Intratumoral expression profiling of genes involved in angiogenesis in colorectal cancer patients treated with chemotherapy plus the VEGFR inhibitor PTK787/ZK 222584 (vatalanib).
PMID: 22664478
Ref: PKB-mediated PHF20 phosphorylation on Ser291 is required for p53 function in DNA damage.
PMID: 22975685
Ref: Tropomyosin-related kinase B promotes distant metastasis of colorectal cancer through protein kinase B-mediated anoikis suppression and correlates with poor prognosis.
PMID: 24549576
Ref: Cbl-b accelerates trypsin-induced cell detachment through ubiquitination and degradation of proline-rich tyrosine kinase 2.
PMID: 25099615
Ref: FAK/PYK2 promotes the Wnt/beta-catenin pathway and intestinal tumorigenesis by phosphorylating GSK3beta.
PMID: 26274564
Ref: Synergistic Effect of SN-38 in Combination with Cetuximab on Angiogenesis and Cancer Cell Invasion.
PMID: 26504021
Ref: Quantitative Profiling of Protein Tyrosine Kinases in Human Cancer Cell Lines by Multiplexed Parallel Reaction Monitoring Assays.
PMID: 26631510
Ref: Localized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted Effects.
PMID: 27224059
Ref: Pathway analysis of expression-related SNPs on genome-wide association study of basal cell carcinoma.
PMID: 27367190
Ref: Exome and transcriptome sequencing identifies loss of PDLIM2 in metastatic colorectal cancers.
PMID: 29184442
Ref: Knockdown of long noncoding RNA urothelial carcinoma associated 1 inhibits colorectal cancer cell proliferation and promotes apoptosis via modulating autophagy.
PMID: 30362538