Primary Site >> Stomach Cancer
Gene >> PTK2
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Ref: EBV-expressing AGS gastric carcinoma cell sublines present increased motility and invasiveness. PMID: 12115496 Ref: Expression of focal adhesion kinase and alpha5 and beta1 integrins in carcinomas and its clinical significance. PMID: 12174366 |
Ref: Involvement of MGr1-Ag/37LRP in the vincristine-induced HIF-1 expression in gastric cancer cells. PMID: 17476462 |
Ref: [Effect of gastrin on tyrosine phosphorylation of focal adhesion kinase in human gastric cancer cell line SGC7901]. PMID: 18184462 |
Ref: Expression and clinical significance of focal adhesion kinase in the two distinct histological types, intestinal and diffuse, of human gastric adenocarcinoma. PMID: 18987997 Ref: SRPX2 is overexpressed in gastric cancer and promotes cellular migration and adhesion. PMID: 19065654 Ref: Signaling components involved in Bcl-w-induced migration of gastric cancer cells. PMID: 19097687 Ref: Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway. PMID: 19625348 Ref: Fibronectin promotes tyrosine phosphorylation of paxillin and cell invasiveness in the gastric cancer cell line AGS. PMID: 20210243 |
Ref: Grp78 promotes the invasion of hepatocellular carcinoma. PMID: 20082722 Ref: Phenethyl isothiocyanate inhibits migration and invasion of human gastric cancer AGS cells through suppressing MAPK and NF-kappaB signal pathways. PMID: 20651362 Ref: Phosphorylation of focal adhesion kinase at Tyr397 in gastric carcinomas and its clinical significance. PMID: 20724588 Ref: Focal adhesion kinase (FAK) gene amplification and its clinical implications in gastric cancer. PMID: 20869748 Ref: CADPE inhibits PMA-stimulated gastric carcinoma cell invasion and matrix metalloproteinase-9 expression by FAK/MEK/ERK-mediated AP-1 activation. PMID: 21047770 |
Ref: Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways. PMID: 20498032 Ref: Periostin expression and epithelial-mesenchymal transition in cancer: a review and an update. PMID: 21997759 |
Ref: Lymphatic endothelial cell-secreted CXCL1 stimulates lymphangiogenesis and metastasis of gastric cancer. PMID: 21387301 Ref: PTP1B expression contributes to gastric cancer progression. PMID: 21442314 Ref: Enterolobium contortisiliquum trypsin inhibitor (EcTI), a plant proteinase inhibitor, decreases in vitro cell adhesion and invasion by inhibition of Src protein-focal adhesion kinase (FAK) signaling pathways. PMID: 22039045 Ref: Sodium butyrate-induced DAPK-mediated apoptosis in human gastric cancer cells. PMID: 22160140 Ref: Inhibitory effects of Yangzheng Xiaoji on angiogenesis and the role of the focal adhesion kinase pathway. PMID: 22971748 Ref: Crosstalk between EGFR and integrin affects invasion and proliferation of gastric cancer cell line, SGC7901. PMID: 23109808 |
Ref: Inhibition of focal adhesion kinase induces apoptosis in human gastric carcinoma cells (SGC-7901). PMID: 23065253 Ref: Antitumor activity of saracatinib (AZD0530), a c-Src/Abl kinase inhibitor, alone or in combination with chemotherapeutic agents in gastric cancer. PMID: 23144237 Ref: High FAK combined with low JWA expression: clinical prognostic and predictive role for adjuvant fluorouracil-leucovorin-oxaliplatin treatment in resectable gastric cancer patients. PMID: 23307041 Ref: Expression of ST3GAL4 leads to SLe(x) expression and induces c-Met activation and an invasive phenotype in gastric carcinoma cells. PMID: 23799130 Ref: Bcl-w Enhances Mesenchymal Changes and Invasiveness of Glioblastoma Cells by Inducing Nuclear Accumulation of beta-Catenin. PMID: 23826359 Ref: Capsosiphon fulvescens glycoprotein reduces AGS gastric cancer cell migration by downregulating transforming growth factor-beta1 and integrin expression. PMID: 23934170 Ref: H. pylori CagL-Y58/E59 prime higher integrin alpha5beta1 in adverse pH condition to enhance hypochlorhydria vicious cycle for gastric carcinogenesis. PMID: 24009701 Ref: Atorvastatin inhibited Rho-associated kinase 1 (ROCK1) and focal adhesion kinase (FAK) mediated adhesion and differentiation of CD133+CD44+ prostate cancer stem cells. PMID: 24177008 |
Ref: PTEN inhibits the invasion and metastasis of gastric cancer via downregulation of FAK expression. PMID: 24486402 Ref: Biglycan enhances gastric cancer invasion by activating FAK signaling pathway. PMID: 24681892 Ref: MGr1-Ag/37LRP induces cell adhesion-mediated drug resistance through FAK/PI3K and MAPK pathway in gastric cancer. PMID: 24703465 Ref: Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway. PMID: 24885567 Ref: Overexpression of Nedd9 is a prognostic marker of human gastric cancer. PMID: 24906654 Ref: Dihydropyrimidinase-like 3 facilitates malignant behavior of gastric cancer. PMID: 25096402 Ref: Lysyl oxidase-like 2 (LOXL2) from stromal fibroblasts stimulates the progression of gastric cancer. PMID: 25128648 |
Ref: Lysyl oxidase-like 4 (LOXL4) promotes proliferation and metastasis of gastric cancer via FAK/Src pathway. PMID: 25216702 Ref: NAIF1 inhibits gastric cancer cells migration and invasion via the MAPK pathways. PMID: 25432142 Ref: Research of shRNAmir inhibitory effects towards focal adhesion kinase expression in the treatment of gastric cancer. PMID: 25621028 Ref: Overexpression of LIMK1 promotes tumor growth and metastasis in gastric cancer. PMID: 25661344 Ref: CEACAM6 promotes tumor angiogenesis and vasculogenic mimicry in gastric cancer via FAK signaling. PMID: 25703140 Ref: Silencing profilin-1 inhibits gastric cancer progression via integrin beta1/focal adhesion kinase pathway modulation. PMID: 25741138 Ref: Role of periostin and its antagonist PNDA-3 in gastric cancer metastasis. PMID: 25759527 Ref: The role of TGFBI (betaig-H3) in gastrointestinal tract tumorigenesis. PMID: 25889002 Ref: ERp19 contributes to tumorigenicity in human gastric cancer by promoting cell growth, migration and invasion. PMID: 25940440 Ref: SRPX2 promotes cell migration and invasion via FAK dependent pathway in pancreatic cancer. PMID: 26191169 Ref: Epigenetic silencing of olfactomedin-4 enhances gastric cancer cell invasion via activation of focal adhesion kinase signaling. PMID: 26303970 Ref: Role of annexin A6 in cancer. PMID: 26622779 |
Ref: CXCL12/CXCR4 activation by cancer-associated fibroblasts promotes integrin beta1 clustering and invasiveness in gastric cancer. PMID: 26414794 Ref: Tumor-suppressive functions of long-chain acyl-CoA synthetase 4 in gastric cancer. PMID: 26949059 Ref: Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems. PMID: 26955870 Ref: TET1 inhibits gastric cancer growth and metastasis by PTEN demethylation and re-expression. PMID: 27121319 Ref: Notch1 pathway-mediated microRNA-151-5p promotes gastric cancer progression. PMID: 27191259 Ref: Effects of combining erlotinib and RNA-interfered downregulation of focal adhesion kinase expression on gastric cancer. PMID: 27278554 Ref: Cbl-b promotes cell detachment via ubiquitination of focal adhesion kinase. PMID: 27446403 Ref: Prognostic Value of Focal Adhesion Kinase (FAK) in Human Solid Carcinomas: A Meta-Analysis. PMID: 27637100 Ref: PFK15, a Small Molecule Inhibitor of PFKFB3, Induces Cell Cycle Arrest, Apoptosis and Inhibits Invasion in Gastric Cancer. PMID: 27669567 |
Ref: CXCL1 from tumor-associated lymphatic endothelial cells drives gastric cancer cell into lymphatic system via activating integrin beta1/FAK/AKT signaling. PMID: 27832972 Ref: High KRT8 expression promotes tumor progression and metastasis of gastric cancer. PMID: 27865045 Ref: Role of miR-647 in human gastric cancer suppression. PMID: 28098914 Ref: Resistance Mechanism against Trastuzumab in HER2-Positive Cancer Cells and Its Negation by Src Inhibition. PMID: 28223426 Ref: KCNMA1 cooperating with PTK2 is a novel tumor suppressor in gastric cancer and is associated with disease outcome. PMID: 28231797 Ref: Long non-coding RNA MALAT1 promotes gastric cancer tumorigenicity and metastasis by regulating vasculogenic mimicry and angiogenesis. PMID: 28268166 Ref: miR-135a inhibits tumor metastasis and angiogenesis by targeting FAK pathway. PMID: 28415713 Ref: Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer. PMID: 28460635 Ref: Cancer-associated fibroblast-derived Lumican promotes gastric cancer progression via the integrin beta1-FAK signaling pathway. PMID: 28542982 Ref: KIF26B, a novel oncogene, promotes proliferation and metastasis by activating the VEGF pathway in gastric cancer. PMID: 28581513 Ref: Downregulation of Notch1 inhibits the invasion and metastasis of human gastric cancer cells SGC7901 and MKN74 in vitro through PTEN activation and dephosphorylation of Akt and FAK. PMID: 28627671 Ref: MicroRNA-379 inhibits metastasis and epithelial-mesenchymal transition via targeting FAK/AKT signaling in gastric cancer. PMID: 28713929 Ref: Calcium-binding protein S100A14 induces differentiation and suppresses metastasis in gastric cancer. PMID: 28726786 Ref: A Comparative Proteomic Analysis of Erinacine A's Inhibition of Gastric Cancer Cell Viability and Invasiveness. PMID: 28854418 Ref: Hypoxia-induced ANGPTL4 sustains tumour growth and anoikis resistance through different mechanisms in scirrhous gastric cancer cell lines. PMID: 28894280 |
Ref: Extracellular matrix protein 1 promotes cell metastasis and glucose metabolism by inducing integrin beta4/FAK/SOX2/HIF-1alpha signaling pathway in gastric cancer. PMID: 29059156 Ref: Regulation of drug resistance and metastasis of gastric cancer cells via the microRNA647-ANK2 axis. PMID: 29328428 Ref: Peiminine serves as an adriamycin chemosensitizer in gastric cancer by modulating the EGFR/FAK pathway. PMID: 29328433 Ref: Merging perspectives: genotype-directed molecular therapy for hereditary diffuse gastric cancer (HDGC) and E-cadherin-EGFR crosstalk. PMID: 29468433 Ref: PTBP3 contributes to the metastasis of gastric cancer by mediating CAV1 alternative splicing. PMID: 29752441 Ref: Netrin1 induces the proliferation of gastric cancer cells via the ERK/MAPK signaling pathway and FAK activation. PMID: 30106432 |