Primary Site >> Colorectal Cancer
Gene >> PTHLH
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Ref: Hypercalcaemia in a patient with fatal adenosquamous carcinoma of the colon. PMID: 8107631 |
Ref: Cloacogenic anal carcinoma presenting with humoral hypercalcemia: report of a case. PMID: 8640024 |
Ref: Parathyroid hormone-related protein expression in the human colon: immunohistochemical evaluation. PMID: 8651548 Ref: Amplification of the parathyroid hormone-related peptide gene in a colonic carcinoma. PMID: 8768840 |
Ref: PTHrP and the PTH/PTHrP receptor are co-expressed in human breast and colon tumours. PMID: 9376272 |
Ref: Clinicopathological implications of parathyroid hormone-related protein in human colorectal tumours. PMID: 10365097 Ref: Humoral hypercalcemia in patients with colorectal carcinoma: report of two cases and review of the literature. PMID: 10590360 |
Ref: Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy. PMID: 10706080 |
Ref: Paraneoplastic hypercalcemia in a patient with adenosquamous cancer of the colon. PMID: 11409809 Ref: Parathyroid hormone-related protein overexpression in the human colon cancer cell line HT-29 enhances adhesion of the cells to collagen type I. PMID: 11495675 Ref: A parathyroid-hormone-related-protein (PTH-rP)-specific cytotoxic T cell response induced by in vitro stimulation of tumour-infiltrating lymphocytes derived from prostate cancer metastases, with epitope peptide-loaded autologous dendritic cells and low-do PMID: 11742494 |
Ref: Breast cancer cells induce osteoclast formation by stimulating host IL-11 production and downregulating granulocyte/macrophage colony-stimulating factor. PMID: 14999770 Ref: The role of the calcium-sensing receptor in cancer. PMID: 15200153 |
Ref: PTH-related protein enhances LoVo colon cancer cell proliferation, adhesion, and integrin expression. PMID: 15582709 Ref: Paraneoplastic hypercalcemia with adenosquamous carcinoma of the colon. PMID: 15864702 Ref: Influence of parathyroid hormone-related peptide gene in colon cancer cell line growth. PMID: 15951855 Ref: Humoral hypercalcemia complicating adenocarcinoma of the sigmoid colon: report of a case. PMID: 16034553 |
Ref: Accumulation profile of frameshift mutations during development and progression of colorectal cancer from patients with hereditary nonpolyposis colorectal cancer. PMID: 16421660 Ref: Roles for the calcium sensing receptor in primary and metastatic cancer. PMID: 16765016 |
Ref: Capecitabine improves cancer cachexia and normalizes IL-6 and PTHrP levels in mouse cancer cachexia models. PMID: 17009035 Ref: Increased cell survival, migration, invasion, and Akt expression in PTHrP-overexpressing LoVo colon cancer cell lines. PMID: 17276526 Ref: PTHrP increases transcriptional activity of the integrin subunit alpha5. PMID: 17406357 Ref: Involvement of cyclooxygenase-2 in the tumor site-dependent production of parathyroid hormone-related protein in colon 26 carcinoma. PMID: 17645771 Ref: PTHrP increases xenograft growth and promotes integrin alpha6beta4 expression and Akt activation in colon cancer. PMID: 17964713 |
Ref: The role of calcium-sensing receptor and signalling pathways in the pathophysiology in two in vitro models of malignant hypercalcemia: the rat rice H-500 Leydig testis cancer and prostate cancer (PC-3) cells. Expression and regulation of pituitary tumor t PMID: 18321443 |
Ref: Calcium-sensing receptor in cancer: good cop or bad cop? PMID: 19011996 Ref: Nuclear PTHrP targeting regulates PTHrP secretion and enhances LoVo cell growth and survival. PMID: 19616583 |
Ref: The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging. PMID: 20227497 Ref: PTHrP promotes colon cancer cell migration and invasion in an integrin alpha6beta4-dependent manner through activation of Rac1. PMID: 20637541 |
Ref: Calcium sensing receptor modulation for cancer therapy. PMID: 23098435 Ref: Hypercalcemia as a Presenting Clinical Manifestation of Adenocarcinoma of the Colon. PMID: 29147304 |
Ref: Cinacalcet attenuates hypercalcemia observed in mice bearing either Rice H-500 Leydig cell or C26-DCT colon tumors. PMID: 23623934 |
Ref: Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH. PMID: 24880666 Ref: Involvement of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways in the regulation of cell cycle progression by PTHrP in colon adenocarcinoma cells. PMID: 25051885 Ref: Molecular mechanisms associated with PTHrP-induced proliferation of colon cancer cells. PMID: 25053227 |
Ref: Hypercalcemia of Malignancy and Colorectal Cancer. PMID: 26998187 |
Ref: RSK activation via ERK modulates human colon cancer cells response to PTHrP. PMID: 28385776 |
Ref: Potential therapeutic targets for growth arrest of colorectal cancer cells exposed to PTHrP. PMID: 30009852 Ref: Interaction between Tumor-Associated Dendritic Cells and Colon Cancer Cells Contributes to Tumor Progression via CXCL1. PMID: 30115896 |