Primary Site >> Colorectal Cancer
Gene >> PTGIS
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Ref: Hypermethylation of the prostacyclin synthase (PTGIS) promoter is a frequent event in colorectal cancer and associated with aneuploidy. PMID: 16007128 |
Ref: Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps. PMID: 16537708 |
Ref: Inhibition of prostaglandin E(2) signaling through the EP(1) receptor does not affect prostacyclin production in human endothelial cells. PMID: 19647091 |
Ref: Overexpression of PTGIS could predict liver metastasis and is correlated with poor prognosis in colon cancer patients. PMID: 22109564 Ref: Combination of haptoglobin and osteopontin could predict colorectal cancer hepatic metastasis. PMID: 22219064 |
Ref: Epigenetics override pro-inflammatory PTGS transcriptomic signature towards selective hyperactivation of PGE2 in colorectal cancer. PMID: 26207152 |