Primary Site >> Stomach Cancer
Gene >> PTEN
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Ref: Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors. PMID: 9458098 |
Ref: Alterations of the PPP1R3 gene in human cancer. PMID: 10485448 |
Ref: Genetic alterations and expression of the protein phosphatase 1 genes in human cancers. PMID: 11251179 |
Ref: Epstein-barr virus-positive gastric carcinoma demonstrates frequent aberrant methylation of multiple genes and constitutes CpG island methylator phenotype-positive gastric carcinoma. PMID: 11891177 Ref: Promoter methylation and silencing of PTEN in gastric carcinoma. PMID: 11896207 Ref: Reduced PTEN expression in gastric cancer and in the gastric mucosa of gastric cancer relatives. PMID: 11953696 Ref: Analysis of genetic and epigenetic alterations of the PTEN gene in gastric cancer. PMID: 11964046 |
Ref: PTEN encoding product: a marker for tumorigenesis and progression of gastric carcinoma. PMID: 12508347 Ref: Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma. PMID: 12569555 Ref: [Expression of PTEN-encoding product in different stages of carcinogenesis and progression of gastric carcinoma]. PMID: 12678979 Ref: Tumour suppressor gene expression correlates with gastric cancer prognosis. PMID: 12692839 Ref: Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in advanced gastric carcinomas. PMID: 12695913 Ref: Growth, invasion, metastasis, differentiation, angiogenesis and apoptosis of gastric cancer regulated by expression of PTEN encoding products. PMID: 12918097 Ref: Role of PTEN and MMP-7 expression in growth, invasion, metastasis and angiogenesis of gastric carcinoma. PMID: 14516315 Ref: Molecular dimensions of gastrointestinal tumors: some thoughts for digestion. PMID: 14518068 |
Ref: Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia. PMID: 14702190 Ref: Pathobiological behavior and molecular mechanism of signet ring cell carcinoma and mucinous adenocarcinoma of the stomach: a comparative study. PMID: 14991954 Ref: [Altered expression of PTEN gene and LOH of its epigenetic microsatellite in gastric carcinoma]. PMID: 15355640 Ref: Inactivation of PTEN is associated with increased angiogenesis and VEGF overexpression in gastric cancer. PMID: 15457582 Ref: [Expressions and activities of Rho GTPases in hypoxia and its relationship with tumor angiogenesis]. PMID: 15555278 Ref: Prognostic significance of CD24 expression in gastric carcinoma. PMID: 20368819 |
Ref: Loss of heterozygosity on 10q23.3 and mutation of tumor suppressor gene PTEN in gastric cancer and precancerous lesions. PMID: 15633233 Ref: COX-2 inhibitor, NS398, enhances Fas-mediated apoptosis via modulation of the PTEN-Akt pathway in human gastric carcinoma cell lines. PMID: 15767780 Ref: Mutations of PIK3CA in gastric adenocarcinoma. PMID: 15784156 Ref: Impact of PTEN on the expression of insulin-like growth factors (IGFs) and IGF-binding proteins in human gastric adenocarcinoma cells. PMID: 15809062 Ref: Suppression of gastric cancer growth by adenovirus-mediated transfer of the PTEN gene. PMID: 15818730 Ref: Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer. PMID: 15900596 Ref: Genetic mutual relationship between PTEN and p53 in gastric cancer. PMID: 16051030 Ref: PTEN expression in non-small-cell lung cancer: evaluating its relation to tumor characteristics, allelic loss, and epigenetic alteration. PMID: 16084946 Ref: [Expression of PTEN and its correlation with angiogenesis in gastric carcinoma]. PMID: 16179839 Ref: PTEN/MMAC1 enhances the growth inhibition by anticancer drugs with downregulation of IGF-II expression in gastric cancer cells. PMID: 16264263 Ref: WNT/PCP signaling pathway and human cancer (review). PMID: 16273260 Ref: Molecular study of the tumour suppressor gene PTEN in gastric adenocarcinoma in Brazil. PMID: 16284736 Ref: Relation of overexpression of S phase kinase-associated protein 2 with reduced expression of p27 and PTEN in human gastric carcinoma. PMID: 16425372 Ref: Potential prognostic significance of p185(HER2) overexpression with loss of PTEN expression in gastric carcinomas. PMID: 16457151 |
Ref: [Correlation of Skp2 expression in gastric carcinoma to expression of P27 and PTEN]. PMID: 16405750 Ref: Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer. PMID: 16482617 Ref: Significance of Survivin and PTEN expression in full lymph node-examined gastric cancer. PMID: 16534839 Ref: Overexpression of hypoxia-inducible factor-1 alpha in gastric adenocarcinoma. PMID: 16557436 Ref: Impact of loss of heterozygosity of encoding phosphate and tensin homolog on the prognosis of gastric cancer. PMID: 16704528 Ref: Expressions of MMP-2, MMP-9 and VEGF are closely linked to growth, invasion, metastasis and angiogenesis of gastric carcinoma. PMID: 17094486 Ref: Reversal of multidrug resistance of gastric cancer cells by downregulation of Akt1 with Akt1 siRNA. PMID: 17310852 |
Ref: Pathobiological characteristics of intestinal and diffuse-type gastric carcinoma in Japan: an immunostaining study on the tissue microarray. PMID: 16714395 Ref: Constitutive phosphorylation of the FOXO1A transcription factor as a prognostic variable in gastric cancer. PMID: 17491598 Ref: [Biological implication of PTEN gene expression in human gastric cancer and related molecular mechanisms]. PMID: 17706140 Ref: Phospho Akt mediates multidrug resistance of gastric cancer cells through regulation of P-gp, Bcl-2 and Bax. PMID: 17725107 Ref: High proportion of large genomic deletions and a genotype phenotype update in 80 unrelated families with juvenile polyposis syndrome. PMID: 17873119 Ref: [Expression and significance of Notch1 and PTEN in gastric cancer]. PMID: 17991315 Ref: Low expression of FHIT and PTEN correlates with malignancy of gastric carcinomas: tissue-array findings. PMID: 18091387 Ref: Homeoprotein Cdx2 and nuclear PTEN expression profiles are related to gastric cancer prognosis. PMID: 18184409 |
Ref: Aberrant Pim-3 expression is involved in gastric adenoma-adenocarcinoma sequence and cancer progression. PMID: 17876606 Ref: Phosphoinositide 3-kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death. PMID: 17935137 Ref: [Reversal of multidrug resistance of gastric cancer cells by down-regulation of CIAPIN1 with CIAPIN1 siRNA]. PMID: 18389626 Ref: PCR-SSCP-DNA sequencing method in detecting PTEN gene mutation and its significance in human gastric cancer. PMID: 18609703 Ref: Mammalian target of rapamycin pathway inhibition enhances the effects of 5-aza-dC on suppressing cell proliferation in human gastric cancer cell lines. PMID: 18622747 Ref: Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas. PMID: 19024597 Ref: PTEN polymorphisms and the risk of esophageal carcinoma and gastric cardiac carcinoma in a high incidence region of China. PMID: 19125794 |
Ref: Phosphatase activity of nuclear PTEN is required for CDX2-mediated intestinal differentiation of gastric carcinoma. PMID: 18996641 Ref: Differential expression of microRNA species in human gastric cancer versus non-tumorous tissues. PMID: 19175831 Ref: Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric carcinoma. PMID: 19339266 Ref: Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library. PMID: 19638344 |
Ref: Vitamin D stimulates apoptosis in gastric cancer cells in synergy with trichostatin A /sodium butyrate-induced and 5-aza-2'-deoxycytidine-induced PTEN upregulation. PMID: 20089040 Ref: A randomized phase III study of adjuvant platinum/docetaxel chemotherapy with or without radiation therapy in patients with gastric cancer. PMID: 20130877 Ref: KRAS mutant lung cancer cells are differentially responsive to MEK inhibitor due to AKT or STAT3 activation: implication for combinatorial approach. PMID: 20358631 Ref: PTEN- and p53-mediated apoptosis and cell cycle arrest by FTY720 in gastric cancer cells and nude mice. PMID: 20506484 Ref: Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway. PMID: 20514448 Ref: Epstein-Barr virus and gastric carcinoma. PMID: 20518883 Ref: 19-peptide, a fragment of tumstatin, inhibits the growth of poorly differentiated gastric carcinoma cells in vitro and in vivo. PMID: 20546447 Ref: MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN. PMID: 20618998 Ref: [The expression and role of PTEN in doxorubicin induced gastric cancer cell apoptosis]. PMID: 20646419 Ref: Constitutive activation of glycogen synthase kinase-3beta correlates with better prognosis and cyclin-dependent kinase inhibitors in human gastric cancer. PMID: 20704706 Ref: Sodium butyrate induces differentiation of gastric cancer cells to intestinal cells via the PTEN/phosphoinositide 3-kinase pathway. PMID: 20718712 Ref: Expression profiling and long lasting responses to chemotherapy in metastatic gastric cancer. PMID: 20878069 Ref: [Construction and identification of gene vector expressing PTEN while simultaneously silencing Livin]. PMID: 21092516 |
Ref: Targeting PI3K/Akt/HSP90 signaling sensitizes gastric cancer cells to deoxycholate-induced apoptosis. PMID: 20585984 Ref: Cetuximab with irinotecan, folinic acid and 5-fluorouracil as first-line treatment in advanced gastroesophageal cancer: a prospective multi-center biomarker-oriented phase II study. PMID: 21119032 Ref: Proteomics-based identification of a group of apoptosis-related proteins and biomarkers in gastric cancer. PMID: 21165559 Ref: Cetuximab enhances the activities of irinotecan on gastric cancer cell lines through downregulating the EGFR pathway upregulated by irinotecan. PMID: 21286718 Ref: Stem cell associated genes working with one miRNA cluster have different clinic pathologic values in gastric cancer. PMID: 21553350 Ref: Down-regulated miRNA-214 induces a cell cycle G1 arrest in gastric cancer cells by up-regulating the PTEN protein. PMID: 21688200 Ref: Lentivirus-mediated RNA interference targeting E2F-1 inhibits human gastric cancer MGC-803 cell growth in vivo. PMID: 21869593 Ref: Epstein-Barr virus-associated gastric carcinoma. PMID: 21944426 |
Ref: microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN. PMID: 22267008 Ref: Regulation of SHP2 by PTEN/AKT/GSK-3beta signaling facilitates IFN-gamma resistance in hyperproliferating gastric cancer. PMID: 22325465 Ref: siRNA targeting of Cdx2 inhibits growth of human gastric cancer MGC-803 cells. PMID: 22563170 Ref: PTEN deletion is rare but often homogeneous in gastric cancer. PMID: 22639407 Ref: Screening and identification of peritoneal metastasis-related genes of gastric adenocarcinoma using a cDNA microarray. PMID: 22782588 Ref: Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile. PMID: 22929309 Ref: Is NEDD4-1 a negative regulator of phosphatase and tensin homolog in gastric carcinogenesis? PMID: 23180960 Ref: Fentanyl inhibits progression of human gastric cancer MGC-803 cells by NF-kappaB downregulation and PTEN upregulation in vitro. PMID: 23193912 Ref: Immunohistochemical expression of mTOR negatively correlates with PTEN expression in gastric carcinoma. PMID: 23205120 |
Ref: Reduced expression of PTEN and increased PTEN phosphorylation at residue Ser380 in gastric cancer tissues: a novel mechanism of PTEN inactivation. PMID: 22521126 Ref: Loss and reduced expression of PTEN correlate with advanced-stage gastric carcinoma. PMID: 23251242 Ref: Increased gastric cancer risk with PTEN IVS4 polymorphism in a Turkish population. PMID: 23402578 Ref: miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN. PMID: 23466500 Ref: MicorRNA 106b approximately 25 cluster and gastric cancer. PMID: 23510949 Ref: PTEN expression and suppression of proliferation are associated with Cdx2 overexpression in gastric cancer cells. PMID: 23546539 Ref: MicroRNA-19a/b regulates multidrug resistance in human gastric cancer cells by targeting PTEN. PMID: 23603256 Ref: AC1MMYR2, an inhibitor of dicer-mediated biogenesis of Oncomir miR-21, reverses epithelial-mesenchymal transition and suppresses tumor growth and progression. PMID: 23811941 Ref: Molecular changes in the phosphatidylinositide 3-kinase (PI3K) pathway are common in gastric cancer. PMID: 23813545 Ref: MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN. PMID: 23834902 Ref: Phase I study of everolimus and mitomycin C for patients with metastatic esophagogastric adenocarcinoma. PMID: 23930209 Ref: Genistein induces G2/M arrest in gastric cancer cells by increasing the tumor suppressor PTEN expression. PMID: 24053672 Ref: Gastric cancer-molecular and clinical dimensions. PMID: 24061039 Ref: The AKT inhibitor AZD5363 is selectively active in PI3KCA mutant gastric cancer, and sensitizes a patient-derived gastric cancer xenograft model with PTEN loss to Taxotere. PMID: 24088382 Ref: miR-106a confers cisplatin resistance by regulating PTEN/Akt pathway in gastric cancer cells. PMID: 24108762 Ref: The AKT1/NF-kappaB/Notch1/PTEN axis has an important role in chemoresistance of gastric cancer cells. PMID: 24113181 Ref: Akt-p53-miR-365-cyclin D1/cdc25A axis contributes to gastric tumorigenesis induced by PTEN deficiency. PMID: 24149576 Ref: High-expression of DJ-1 and loss of PTEN associated with tumor metastasis and correlated with poor prognosis of gastric carcinoma. PMID: 24155657 |
Ref: Phosphatidylinositol-3-kinase pathway aberrations in gastric and colorectal cancer: meta-analysis, co-occurrence and ethnic variation. PMID: 23960014 Ref: The microRNA-21/PTEN pathway regulates the sensitivity of HER2-positive gastric cancer cells to trastuzumab. PMID: 24154840 Ref: Upregulated microRNA-301a in breast cancer promotes tumor metastasis by targeting PTEN and activating Wnt/beta-catenin signaling. PMID: 24315818 Ref: miR-338-3p suppresses gastric cancer progression through a PTEN-AKT axis by targeting P-REX2a. PMID: 24375644 Ref: Expression of B-cell-specific Moloney murine leukemia virus integration site 1 mRNA and protein in gastric cancer. PMID: 24393364 Ref: The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway. PMID: 24416349 Ref: HER2 expression and PI3K-Akt pathway alterations in gastric cancer. PMID: 24458107 Ref: PTEN inhibits the invasion and metastasis of gastric cancer via downregulation of FAK expression. PMID: 24486402 Ref: Roles of PTEN (Phosphatase and Tensin Homolog) in gastric cancer development and progression. PMID: 24528021 Ref: Clinical and prognostic significance of HIF-1alpha, PTEN, CD44v6, and survivin for gastric cancer: a meta-analysis. PMID: 24647137 Ref: MicroRNA-21 stimulates gastric cancer growth and invasion by inhibiting the tumor suppressor effects of programmed cell death protein 4 and phosphatase and tensin homolog. PMID: 24659669 Ref: Prognostic impact of gastrointestinal bleeding and expression of PTEN and Ki-67 on primary gastrointestinal stromal tumors. PMID: 24712384 Ref: A GG allele of 3'-side AKT1 SNP is associated with decreased AKT1 activation and better prognosis of gastric cancer. PMID: 24737346 Ref: MicroRNA-106b in cancer-associated fibroblasts from gastric cancer promotes cell migration and invasion by targeting PTEN. PMID: 24842611 Ref: The PI3K/AKT/mTOR pathway is activated in gastric cancer with potential prognostic and predictive significance. PMID: 24844205 Ref: MicroRNA-382 induced by HIF-1alpha is an angiogenic miR targeting the tumor suppressor phosphatase and tensin homolog. PMID: 24914051 Ref: Long noncoding RNA associated-competing endogenous RNAs in gastric cancer. PMID: 25124853 Ref: [MiR-425 up-regulation induced by interleukin-1beta promotes the proliferation of gastric cancer cell AGS]. PMID: 25154996 Ref: Phosphorylated insulin-like growth factor-1 receptor expression predicts poor prognosis of Chinese patients with gastric cancer. PMID: 25348345 Ref: An increase in integrin-linked kinase non-canonically confers NF-kappaB-mediated growth advantages to gastric cancer cells by activating ERK1/2. PMID: 25398317 Ref: Ursolic acid promotes apoptosis of SGC-7901 gastric cancer cells through ROCK/PTEN mediated mitochondrial translocation of cofilin-1. PMID: 25520072 |
Ref: WWP1 as a potential tumor oncogene regulates PTEN-Akt signaling pathway in human gastric carcinoma. PMID: 25293520 Ref: PTEN deficiency as a predictive biomarker of resistance to HER2-targeted therapy in advanced gastric cancer. PMID: 25300346 Ref: Baicalein reverses hypoxia-induced 5-FU resistance in gastric cancer AGS cells through suppression of glycolysis and the PTEN/Akt/HIF-1alpha signaling pathway. PMID: 25333894 Ref: Loss of heterozygosity of PTEN (encoding phosphate and tensin homolog) associated with elevated HER2 expression is an adverse prognostic indicator in gastric cancer. PMID: 25472613 Ref: SOX2, a predictor of survival in gastric cancer, inhibits cell proliferation and metastasis by regulating PTEN. PMID: 25543086 Ref: Overexpression of CDX2 in gastric cancer cells promotes the development of multidrug resistance. PMID: 25628941 Ref: The functional sites of miRNAs and lncRNAs in gastric carcinogenesis. PMID: 25636450 Ref: CDX2 inhibits invasion and migration of gastric cancer cells by phosphatase and tensin homologue deleted from chromosome 10/Akt signaling pathway. PMID: 25881601 Ref: Metformin potentiates rapamycin and cisplatin in gastric cancer in mice. PMID: 25909163 Ref: MicroRNA-377 predicts poor clinical outcome of gastric cancer and induces tumorigenesis by targeting multiple tumor-suppressor genes. PMID: 25998046 Ref: alpha-Fetoprotein-Producing Hepatoid Gastric Adenocarcinoma With Osteoclast-Like Giant Cells and Neuroendocrine Differentiation: A Case Study With Molecular Profiling. PMID: 26009570 Ref: Development of trastuzumab-resistant human gastric carcinoma cell lines and mechanisms of drug resistance. PMID: 26108989 Ref: Role of Delta133p53 in Tumor Necrosis Factor-induced survival of p53 functions in MKN45 gastric cancer cell line. PMID: 26214777 Ref: Patient-Derived Gastric Carcinoma Xenograft Mouse Models Faithfully Represent Human Tumor Molecular Diversity. PMID: 26217940 Ref: Long noncoding RNA FER1L4 suppresses cancer cell growth by acting as a competing endogenous RNA and regulating PTEN expression. PMID: 26306906 Ref: ODAM inhibits RhoA-dependent invasion in breast cancer. PMID: 26358398 Ref: Expression of Fatty Acid Synthase Negatively Correlates with PTEN and Predicts Peritoneal Dissemination of Human Gastric Cancer. PMID: 26514456 Ref: Cytotoxic effects of beta-carboline alkaloids on human gastric cancer SGC-7901 cells. PMID: 26550217 Ref: GX1-mediated anionic liposomes carrying adenoviral vectors for enhanced inhibition of gastric cancer vascular endothelial cells. PMID: 26570987 Ref: Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine? PMID: 26604635 Ref: miR-21 inhibits the effects of cyclooxygenase-2 inhibitor NS398 on apoptosis and invasion in gastric cancer cells. PMID: 26604791 Ref: Osteoprotegerin secreted by inflammatory and invasive breast cancer cells induces aneuploidy, cell proliferation and angiogenesis. PMID: 26608463 |
Ref: Activation of nuclear PTEN by inhibition of Notch signaling induces G2/M cell cycle arrest in gastric cancer. PMID: 25823029 Ref: Pseudogene PTENP1 Suppresses Gastric Cancer Progression by Modulating PTEN. PMID: 25968876 Ref: Resveratrol induces cell cycle arrest in human gastric cancer MGC803 cells via the PTEN-regulated PI3K/Akt signaling pathway. PMID: 26530632 Ref: Synergistic tumor suppression by adenovirus-mediated ING4/PTEN double gene therapy for gastric cancer. PMID: 26564429 Ref: Downregulation of microRNA-193-3p inhibits tumor proliferation migration and chemoresistance in human gastric cancer by regulating PTEN gene. PMID: 26753960 Ref: New Functions of the Inositol Polyphosphate 5-Phosphatases in Cancer. PMID: 26916021 Ref: An increase in galectin-3 causes cellular unresponsiveness to IFN-gamma-induced signal transduction and growth inhibition in gastric cancer cells. PMID: 26934444 Ref: The roles of HOXB7 in promoting migration, invasion, and anti-apoptosis in gastric cancer. PMID: 26968988 Ref: Sleeping Beauty transposon mutagenesis identifies genes that cooperate with mutant Smad4 in gastric cancer development. PMID: 27006499 Ref: Antitumor activity and inhibitory effects on cancer stem cell-like properties of Adeno-associated virus (AAV) -mediated Bmi-1 interference driven by Bmi-1 promoter for gastric cancer. PMID: 27009837 Ref: TET1 inhibits gastric cancer growth and metastasis by PTEN demethylation and re-expression. PMID: 27121319 Ref: The Gene Expression Status of the PI3K/AKT/mTOR Pathway in Gastric Cancer Tissues and Cell Lines. PMID: 27156070 Ref: Significance of microRNA 21 in gastric cancer. PMID: 27179559 Ref: Biomarkers of EBV-positive Gastric Cancers: Loss of PTEN Expression is Associated with Poor Prognosis and Nodal Metastasis. PMID: 27221363 Ref: The Inositide Signaling Pathway As a Target for Treating Gastric Cancer and Colorectal Cancer. PMID: 27242542 Ref: Comprehensive expression profiles of gastric cancer molecular subtypes by immunohistochemistry: implications for individualized therapy. PMID: 27331626 Ref: MicroRNA-214 promotes peritoneal metastasis through regulating PTEN negatively in gastric cancer. PMID: 27339596 Ref: Upregulation of microRNA-370 promotes cell apoptosis and inhibits proliferation by targeting PTEN in human gastric cancer. PMID: 27499479 Ref: PRL-3 promotes the peritoneal metastasis of gastric cancer through the PI3K/Akt signaling pathway by regulating PTEN. PMID: 27572739 Ref: MicroRNA-21 promotes TGF-beta1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expression. PMID: 27611950 Ref: Bmi-1 regulates stem cell-like properties of gastric cancer cells via modulating miRNAs. PMID: 27644439 Ref: Geridonin and paclitaxel act synergistically to inhibit the proliferation of gastric cancer cells through ROS-mediated regulation of the PTEN/PI3K/Akt pathway. PMID: 27659528 Ref: Upregulation of miR-222 in both Helicobacter pylori- infected and noninfected gastric cancer patients. PMID: 27994199 |
Ref: MicroRNA-221-3p Plays an Oncogenic Role in Gastric Carcinoma by Inhibiting PTEN Expression. PMID: 27712596 Ref: Distinct expression profile of key molecules in crawling-type early gastric carcinoma. PMID: 27734272 Ref: Altered mitochondrial quality control signaling in muscle of old gastric cancer patients with cachexia. PMID: 27847330 Ref: Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma. PMID: 27898655 Ref: Discordance of Somatic Mutations Between Asian and Caucasian Patient Populations with Gastric Cancer. PMID: 28039579 Ref: Resveratrol reverses Doxorubicin resistance by inhibiting epithelial-mesenchymal transition (EMT) through modulating PTEN/Akt signaling pathway in gastric cancer. PMID: 28126034 Ref: Long non-coding RNA PTENP1 functions as a ceRNA to modulate PTEN level by decoying miR-106b and miR-93 in gastric cancer. PMID: 28212532 Ref: MiR-26a performs converse roles in proliferation and metastasis of different gastric cancer cells via regulating of PTEN expression. PMID: 28242043 Ref: Immunohistochemical analysis of PTEN, HER2/neu, and ki67 expression in patients with gastric cancer and their association with survival. PMID: 28262306 Ref: Expression and function of Uc.160+, a transcribed ultraconserved region, in gastric cancer. PMID: 28382457 Ref: CtBP2 overexpression promotes tumor cell proliferation and invasion in gastric cancer and is associated with poor prognosis. PMID: 28404932 Ref: Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells. PMID: 28407783 Ref: Complementary utility of targeted next-generation sequencing and immunohistochemistry panels as a screening platform to select targeted therapy for advanced gastric cancer. PMID: 28418920 Ref: Long Noncoding RNA AFAP1-AS1 Promotes Cell Proliferation and Apoptosis of Gastric Cancer Cells via PTEN/p-AKT Pathway. PMID: 28451917 Ref: Downregulation of Notch1 inhibits the invasion and metastasis of human gastric cancer cells SGC7901 and MKN74 in vitro through PTEN activation and dephosphorylation of Akt and FAK. PMID: 28627671 Ref: Role of ARPC2 in Human Gastric Cancer. PMID: 28694563 Ref: Effect of operating room care combined with home care for the postoperative rehabilitation and prognosis of gastric cancer patients with low PTEN gene expression. PMID: 28781652 Ref: Protein Expression of Programmed Death 1 Ligand 1 and HER2 in Gastric Carcinoma. PMID: 28910818 Ref: Downregulation of MicroRNA-147 Inhibits Cell Proliferation and Increases the Chemosensitivity of Gastric Cancer Cells to 5-Fluorouracil by Directly Targeting PTEN. PMID: 28950928 Ref: Esophageal Adenocarcinoma-Derived Extracellular Vesicle MicroRNAs Induce a Neoplastic Phenotype in Gastric Organoids. PMID: 28968550 Ref: Enhanced antiproliferative activity of antibody-functionalized polymeric nanoparticles for targeted delivery of anti-miR-21 to HER2 positive gastric cancer. PMID: 28978026 Ref: PTEN Gene Induces Cell Invasion and Migration via Regulating AKT/GSK-3beta/beta-Catenin Signaling Pathway in Human Gastric Cancer. PMID: 29030742 Ref: The GAS5/miR-222 Axis Regulates Proliferation of Gastric Cancer Cells Through the PTEN/Akt/mTOR Pathway. PMID: 29098549 Ref: Downregulation of HADH promotes gastric cancer progression via Akt signaling pathway. PMID: 29100311 Ref: Enhancing conventional chemotherapy drug cisplatin-induced anti-tumor effects on human gastric cancer cells both in vitro and in vivo by Thymoquinone targeting PTEN gene. PMID: 29156767 Ref: Prognostic implications of phosphatidylinositol 3-kinase/AKT signaling pathway activation in gastric carcinomas. PMID: 29181056 Ref: Strengthening Gastric Cancer Therapy by Trastuzumab-Conjugated Nanoparticles with Simultaneous Encapsulation of Anti-MiR-21 and 5-Fluorouridine. PMID: 29241186 Ref: Kruppel-like factor 2 suppresses human gastric tumorigenesis through inhibiting PTEN/AKT signaling. PMID: 29245984 Ref: PTEN loss and level of HER2 amplification is associated with trastuzumab resistance and prognosis in HER2-positive gastric cancer. PMID: 29371924 |
Ref: Overexpression of Circular RNA ciRS-7 Abrogates the Tumor Suppressive Effect of miR-7 on Gastric Cancer via PTEN/PI3K/AKT Signaling Pathway. PMID: 28608528 Ref: Gastric poorly cohesive carcinoma: a correlative study of mutational signatures and prognostic significance based on histopathological subtypes. PMID: 28873240 Ref: MicroRNA-197 inhibits gastric cancer progression by directly targeting metadherin. PMID: 29115517 Ref: VDR independent induction of acid-sphingomyelinase by 1,23(OH)2 D3 in gastric cancer cells: Impact on apoptosis and cell morphology. PMID: 29158006 Ref: miR-21 Inhibitors Modulate Biological Functions of Gastric Cancer Cells via PTEN/PI3K/mTOR Pathway. PMID: 29185784 Ref: MicroRNA-28 promotes cell proliferation and invasion in gastric cancer via the PTEN/PI3K/AKT signalling pathway. PMID: 29257342 Ref: F-box protein 11 promotes the growth and metastasis of gastric cancer via PI3K/AKT pathway-mediated EMT. PMID: 29278851 Ref: Serum microRNA panel excavated by machine learning as a potential biomarker for the detection of gastric cancer. PMID: 29286167 Ref: Depletion of S100A4(+) stromal cells does not prevent HCC development but reduces the stem cell-like phenotype of the tumors. PMID: 29303514 Ref: The polycomb group protein EZH2 induces epithelial-mesenchymal transition and pluripotent phenotype of gastric cancer cells by binding to PTEN promoter. PMID: 29335012 Ref: Long non-coding RNA GPR65-1 is up-regulated in gastric cancer and promotes tumor growth through the PTEN-AKT-slug signaling pathway. PMID: 29336198 Ref: Circular RNA-ZFR Inhibited Cell Proliferation and Promoted Apoptosis in Gastric Cancer by Sponging miR-130a/miR-107 and Modulating PTEN. PMID: 29361817 Ref: miR215p confers doxorubicin resistance in gastric cancer cells by targeting PTEN and TIMP3. PMID: 29393355 Ref: Interference of P-REX2a may inhibit proliferation and reverse the resistance of SGC7901 cells to doxorubicin. PMID: 29435055 Ref: Concomitant modulation of PTEN and Livin in gastric cancer treatment. PMID: 29436592 Ref: Overexpression of Lymphocyte Antigen 6 Complex, Locus E in Gastric Cancer Promotes Cancer Cell Growth and Metastasis. PMID: 29448250 Ref: The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells. PMID: 29455656 Ref: Low expression of PTEN is essential for maintenance of a malignant state in human gastric adenocarcinoma via upregulation of pAURKA mediated by activation of AURKA. PMID: 29512701 Ref: Prader-Willi region non-protein coding RNA 1 suppressed gastric cancer growth as a competing endogenous RNA of miR-425-5p. PMID: 29535266 Ref: Microrna-136 promotes proliferation and invasion ingastric cancer cells through Pten/Akt/P-Akt signaling pathway. PMID: 29541241 Ref: Long non-coding RNA SNHG14 contributes to gastric cancer development through targeting miR-145/SOX9 axis. PMID: 29667771 Ref: miRNA-21 promotes gastric cancer growth by adjusting prostaglandin E2. PMID: 29687845 Ref: Genomic Profiling of HER2-Positive Gastric Cancer: PI3K/Akt/mTOR Pathway as Predictor of Outcomes in HER2-Positive Advanced Gastric Cancer Treated with Trastuzumab. PMID: 29700210 Ref: MiR-616-3p promotes angiogenesis and EMT in gastric cancer via the PTEN/AKT/mTOR pathway. PMID: 29777710 Ref: Expression of microRNAs and IRAK1 pathway genes are altered in gastric cancer patients with Helicobacter pylori infection. PMID: 29797599 Ref: Dysregulation of microRNA23b3p contributes to the development of intracranial aneurysms by targeting phosphatase and tensin homolog. PMID: 29845190 Ref: Ataxin-3 promotes testicular cancer cell proliferation by inhibiting anti-oncogene PTEN. PMID: 29902454 Ref: Metastasis suppressor protein 1 regulated by PTEN suppresses invasion, migration, and EMT of gastric carcinoma by inactivating PI3K/AKT signaling. PMID: 30013632 Ref: High miR-718 Suppresses Phosphatase and Tensin Homolog (PTEN) Expression and Correlates to Unfavorable Prognosis in Gastric Cancer. PMID: 30131483 Ref: PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis. PMID: 30134988 Ref: Three types of metaplasia models through Kras activation, Pten deletion, or Cdh1 deletion in the gastric epithelium. PMID: 30168144 Ref: Metastasis suppressor protein 1 regulated by PTEN suppresses invasion, migration, and EMT of gastric carcinoma by inactivating PI3K/AKT signaling. PMID: 30246429 Ref: Helicobacter pylori promotes gastric epithelial cell survival through the PLK1/PI3K/Akt pathway. PMID: 30254463 Ref: F-box and leucine-rich repeat protein 5 promotes colon cancer progression by modulating PTEN/PI3K/AKT signaling pathway. PMID: 30257389 Ref: Long noncoding RNA HOTAIRM1 inhibits cell progression by regulating miR-17-5p/ PTEN axis in gastric cancer. PMID: 30302796 Ref: Transcribed ultraconserved noncoding RNA uc.160 acts as a negative regulator in gastric cancer. PMID: 30323869 Ref: The contrary functions of lncRNA HOTAIR/miR-17-5p/PTEN axis and Shenqifuzheng injection on chemosensitivity of gastric cancer cells. PMID: 30338929 |