Primary Site >> Colorectal Cancer
Gene >> PSMB8
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Ref: Functional deficiencies of components of the MHC class I antigen pathway in human tumors of epithelial origin. PMID: 10933198 |
Ref: Total loss of MHC class I in colorectal tumors can be explained by two molecular pathways: beta2-microglobulin inactivation in MSI-positive tumors and LMP7/TAP2 downregulation in MSI-negative tumors. PMID: 12694570 |
Ref: Promyelocytic leukemia (PML) nuclear bodies are disorganized in colorectal tumors with total loss of major histocompatibility complex class I expression and LMP7 downregulation. PMID: 15104675 |
Ref: Correlation between expression of major histocompatibility complex class I and that of antigen presenting machineries in carcinoma cell lines of the pancreas, biliary tract and colon. PMID: 16855371 |
Ref: Chemotherapeutic agents in low noncytotoxic concentrations increase immunogenicity of human colon cancer cells. PMID: 21290210 Ref: Methylation-specific ligation detection reaction (msLDR): a new approach for multiplex evaluation of methylation patterns. PMID: 21879293 Ref: The LMP7-K allele of the immunoproteasome exhibits reduced transcript stability and predicts high risk of colon cancer. PMID: 22037870 |
Ref: PSMB8 as a Candidate Marker of Responsiveness to Preoperative Radiation Therapy in Rectal Cancer Patients. PMID: 28721901 Ref: Inhibition and deficiency of the immunoproteasome subunit LMP7 suppress the development and progression of colorectal carcinoma in mice. PMID: 28881611 |