Primary Site >> Colorectal Cancer
Gene >> PSEN1
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Ref: Presenilin-dependent "gamma-secretase" processing of deleted in colorectal cancer (DCC). PMID: 12840034 |
Ref: Presenilin attenuates receptor-mediated signaling and synaptic function. PMID: 15703408 Ref: Spatial segregation of gamma-secretase and substrates in distinct membrane domains. PMID: 15886206 |
Ref: Pulmonary metastasectomy for colorectal cancer: weak evidence and no randomised trials. PMID: 18065234 |
Ref: Site-dependent E-cadherin cleavage and nuclear translocation in a metastatic colorectal cancer model. PMID: 20813963 Ref: Gamma-secretase complexes regulate the responses of human pancreatic ductal adenocarcinoma cells to taxanes. PMID: 21187481 |
Ref: Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells. PMID: 21678067 |
Ref: Paradoxical E-cadherin increase in 5FU-resistant colon cancer is unaffected during mesenchymal-epithelial reversion induced by gamma-secretase inhibition. PMID: 26746659 Ref: Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer. PMID: 27245242 |