Primary Site >> Biliary tract Cancer
Gene >> PSCA
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Ref: Prostate stem cell antigen, a presumable organ-dependent tumor suppressor gene, is down-regulated in gallbladder carcinogenesis. PMID: 21936014 Ref: Prostate stem cell antigen gene is expressed in islets of pancreas. PMID: 23094202 |
Ref: Missense allele of a single nucleotide polymorphism rs2294008 attenuated antitumor effects of prostate stem cell antigen in gallbladder cancer cells. PMID: 23599686 Ref: PSCA and Oct-4 expression in the benign and malignant lesions of gallbladder: implication for carcinogenesis, progression, and prognosis of gallbladder adenocarcinoma. PMID: 23984394 Ref: PSCA gene variants (rs2294008 and rs2978974) confer increased susceptibility of gallbladder carcinoma in females. PMID: 23988503 |
Ref: rs2294008T, a risk allele for gastric and gallbladder cancers, suppresses the PSCA promoter by recruiting the transcription factor YY1. PMID: 25727947 Ref: Down-regulation of Immune-related Genes by PSCA in Gallbladder Cancer Cells Implanted into Mice. PMID: 25964537 Ref: A Multiple Interaction Analysis Reveals ADRB3 as a Potential Candidate for Gallbladder Cancer Predisposition via a Complex Interaction with Other Candidate Gene Variations. PMID: 26602921 |