Primary Site >> Liver Cancer

Gene >> PROX1

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Ref: A homeobox protein, prox1, is involved in the differentiation, proliferation, and prognosis in hepatocellular carcinoma.
PMID: 17062673
 Ref: Altered regulation of Prox1-gene-expression in liver tumors.
PMID: 18400094
 Ref: Transcriptional repression of TWIST1 gene by Prospero-related homeobox 1 inhibits invasiveness of hepatocellular carcinoma cells.
PMID: 22982861
 Ref: The homeobox transcription factor Prox1 inhibits proliferation of hepatocellular carcinoma cells by inducing p53-dependent senescence-like phenotype.
PMID: 23291986
Ref: PROX1 promotes hepatocellular carcinoma metastasis by way of up-regulating hypoxia-inducible factor 1alpha expression and protein stability.
PMID: 23505027
Ref: Multitargeting and antimetastatic potentials of silibinin in human HepG-2 and PLC/PRF/5 hepatoma cells.
PMID: 23659451
 Ref: PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing beta-catenin expression and nuclear translocation.
PMID: 25684142
 Ref: MiR-670-5p induces cell proliferation in hepatocellular carcinoma by targeting PROX1.
PMID: 26796260
 Ref: Prospero-related homeobox 1 drives angiogenesis of hepatocellular carcinoma through selectively activating interleukin-8 expression.
PMID: 28646551
 Ref: Suppression of PROX1-mediated TERT expression in hepatitis B viral hepatocellular carcinoma.
PMID: 29987895
Ref: Analysis of The Cancer Genome Atlas data to determine the correlation between PROX1 and TERT in hepatocellular carcinoma.
PMID: 30246869