Primary Site >> Colorectal Cancer
Gene >> PROM1
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Ref: Differential CD146 expression on circulating versus tissue endothelial cells in rectal cancer patients: implications for circulating endothelial and progenitor cells as biomarkers for antiangiogenic therapy. PMID: 16549839 Ref: The migrating cancer stem cells model--a conceptual explanation of malignant tumour progression. PMID: 17939298 |
Ref: Identification and expansion of human colon-cancer-initiating cells. PMID: 17122771 Ref: A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. PMID: 17122772 Ref: Comparative genomics on PROM1 gene encoding stem cell marker CD133. PMID: 17487431 Ref: Elevated circulating endothelial progenitor marker CD133 messenger RNA levels predict colon cancer recurrence. PMID: 17594720 Ref: Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4. PMID: 18371377 |
Ref: Biological and genetic characteristics of tumor-initiating cells in colon cancer. PMID: 17932721 Ref: IL-4-mediated drug resistance in colon cancer stem cells. PMID: 18235245 Ref: [Spheres isolated from Colo205 cell line possess cancer stem-like cells under serum-free culture condition]. PMID: 18250051 Ref: Is CD133 a marker of metastatic colon cancer stem cells? PMID: 18497883 Ref: CD133 expression is not restricted to stem cells, and both CD133+ and CD133- metastatic colon cancer cells initiate tumors. PMID: 18497886 Ref: Crucial role of interleukin-4 in the survival of colon cancer stem cells. PMID: 18519657 Ref: CD133+CD44+ population efficiently enriches colon cancer initiating cells. PMID: 18663533 Ref: Immunohistochemical detection of CD133 expression in colorectal cancer: a clinicopathological study. PMID: 18754869 Ref: Quantification of circulating endothelial and progenitor cells: comparison of quantitative PCR and four-channel flow cytometry. PMID: 18755033 Ref: Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity. PMID: 18765800 Ref: CD133 expression is an independent prognostic marker for low survival in colorectal cancer. PMID: 18781171 Ref: Cell cycle-dependent variation of a CD133 epitope in human embryonic stem cell, colon cancer, and melanoma cell lines. PMID: 18829544 Ref: Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. PMID: 18829568 Ref: CD44 is of functional importance for colorectal cancer stem cells. PMID: 18980968 Ref: Immunostaining of Lgr5, an intestinal stem cell marker, in normal and premalignant human gastrointestinal tissue. PMID: 19030762 |
Ref: Cancer stem cell marker expression in hepatocellular carcinoma and liver metastases is not sufficient as single prognostic parameter. PMID: 19026485 Ref: Characterization of a subpopulation of colon cancer cells with stem cell-like properties. PMID: 19072981 Ref: The first extracellular domain of the tumour stem cell marker CD133 contains an antigenic ganglioside-binding motif. PMID: 19216024 Ref: Expression of gastrin precursors by CD133-positive colorectal cancer cells is crucial for tumour growth. PMID: 19321126 Ref: CD133 and nuclear beta-catenin: the marker combination to detect high risk cases of low stage colorectal cancer. PMID: 19403300 Ref: Cancer stem cell markers CD133 and CD24 correlate with invasiveness and differentiation in colorectal adenocarcinoma. PMID: 19437567 Ref: Phenotypic subpopulations of metastatic colon cancer stem cells: genomic analysis. PMID: 19451087 Ref: Demethylation of the CD133 gene is frequently detected in advanced colorectal cancer. PMID: 19528487 Ref: Isolation and characterization of CD133+ cell population within human primary and metastatic colon cancer. PMID: 19530513 Ref: Type I collagen inhibits differentiation and promotes a stem cell-like phenotype in human colorectal carcinoma cells. PMID: 19568234 Ref: Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB. PMID: 19583834 Ref: Newly characterised ex vivo colospheres as a three-dimensional colon cancer cell model of tumour aggressiveness. PMID: 19603013 Ref: The cancer stem cell marker CD133 has high prognostic impact but unknown functional relevance for the metastasis of human colon cancer. PMID: 19621338 Ref: Prognostic significance of the cancer stem cell markers CD133, CD44, and CD166 in colorectal cancer. PMID: 19626493 Ref: Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. PMID: 19657699 Ref: CD133 expression is not selective for tumor-initiating or radioresistant cell populations in the CRC cell lines HCT-116. PMID: 19699546 Ref: Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel. PMID: 19699770 Ref: Cancer stem cell marker CD133+ tumour cells and clinical outcome in rectal cancer. PMID: 19723143 Ref: Elevated CD133, but not VEGF or EGFR, as a predictive marker of distant recurrence after preoperative chemoradiotherapy in rectal cancer. PMID: 19724847 Ref: Maintenance of HCT116 colon cancer cell line conforms to a stochastic model but not a cancer stem cell model. PMID: 19737148 Ref: CD133 gene overexpression is frequently observed in early colorectal carcinoma. PMID: 19760928 Ref: Elimination of Colon Cancer Stem-Like Cells by the Combination of Curcumin and FOLFOX. PMID: 19956394 Ref: Colorectal cancer stem cells. PMID: 19966616 Ref: New Therapeutics Targeting Colon Cancer Stem Cells. PMID: 20148131 |
Ref: Tumour CD133 mRNA expression and clinical outcome in surgically resected colorectal cancer patients. PMID: 20005089 Ref: Expression of CD133 correlates with differentiation of human colon cancer cells. PMID: 20023382 Ref: CD133 expression predicts for non-response to chemotherapy in colorectal cancer. PMID: 20081809 Ref: ABCG5-positivity in tumor buds is an indicator of poor prognosis in node-negative colorectal cancer patients. PMID: 20135722 Ref: Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks. PMID: 20167130 Ref: Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers. PMID: 20176655 Ref: Effects of heterochromatin in colorectal cancer stem cells on radiosensitivity. PMID: 20193109 Ref: CD133 expression in rectal cancer after preoperative chemoradiotherapy. PMID: 20219069 Ref: In situ protein expression in tumour spheres: development of an immunostaining protocol for confocal microscopy. PMID: 20307308 Ref: Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery. PMID: 20332776 Ref: Post-translational modulation of CD133 expression during sodium butyrate-induced differentiation of HT29 human colon cancer cells: implications for its detection. PMID: 20333645 Ref: CD133 expression is not selective for tumor-initiating or radioresistant cell populations in the CRC cell line HCT-116. PMID: 20344822 Ref: The percentage of CD133+ cells in human colorectal cancer cell lines is influenced by Mycoplasma hyorhinis infection. PMID: 20353562 Ref: CD133 expression is a potential prognostic indicator in intrahepatic cholangiocarcinoma. PMID: 20379837 Ref: Colon cancer stem cells: promise of targeted therapy. PMID: 20420952 Ref: Copper-64-diacetyl-bis (N4-methylthiosemicarbazone) accumulates in rich regions of CD133+ highly tumorigenic cells in mouse colon carcinoma. PMID: 20447549 Ref: Quantitative analyses of CD133 expression facilitate researches on tumor stem cells. PMID: 20460748 Ref: The stem cell marker CD133 associates with enhanced colony formation and cell motility in colorectal cancer. PMID: 20502714 Ref: Demethylation of the CD133 gene is frequently detected in early gastric carcinoma. PMID: 20530428 Ref: Activation of Akt and MAPK pathways enhances the tumorigenicity of CD133+ primary colon cancer cells. PMID: 20530554 Ref: Characteristics of CD133(+) human colon cancer SW620 cells. PMID: 20587144 Ref: Isolation and propagation of a human CD133(-) colon tumor-derived cell line with tumorigenic and angiogenic properties. PMID: 20587145 Ref: Establishment and biological characteristics of oxaliplatin-resistant human colon cancer cell lines. PMID: 20591218 Ref: Promoter hypermethylation and loss of CD133 gene expression in colorectal cancers. PMID: 20593500 Ref: Immunohistochemical features of CD133 expression: association with resistance to chemoradiotherapy in rectal cancer. PMID: 20596619 Ref: Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer. PMID: 20606680 Ref: Predictive value of cancer stem-like cells and cancer-associated genetic markers for peritoneal recurrence of colorectal cancer in patients after curative surgery. PMID: 20616575 Ref: CD133(+) single cell-derived progenies of colorectal cancer cell line SW480 with different invasive and metastatic potential. PMID: 20617370 Ref: New-generation taxoid SB-T-1214 inhibits stem cell-related gene expression in 3D cancer spheroids induced by purified colon tumor-initiating cells. PMID: 20630067 Ref: Prospectively isolated cancer-associated CD10(+) fibroblasts have stronger interactions with CD133(+) colon cancer cells than with CD133(-) cancer cells. PMID: 20711432 Ref: Anti-human CD133 monoclonal antibody that could inhibit the proliferation of colorectal cancer cells. PMID: 20715988 Ref: Toll-like receptor (TLR) 7 and TLR8 expression on CD133+ cells in colorectal cancer points to a specific role for inflammation-induced TLRs in tumourigenesis and tumour progression. PMID: 20728343 Ref: 5-Fluorouracil upregulates the activity of Wnt signaling pathway in CD133-positive colon cancer stem-like cells. PMID: 20800023 Ref: CD133 mRNA expression and microsatellite instability in colorectal carcinoma. PMID: 20872808 Ref: Frequency and pattern of expression of the stem cell marker CD133 have strong prognostic effect on the surgical outcome of colorectal cancer patients. PMID: 20878111 Ref: Automated analysis of protein expression and gene amplification within the same cells of paraffin-embedded tumour tissue. PMID: 20966547 Ref: Differential expression of aldehyde dehydrogenase 1a1 (ALDH1) in normal ovary and serous ovarian tumors. PMID: 21176222 Ref: Proliferation characteristics of CD133+ cell population in colorectal cancer. PMID: 21181366 Ref: Non-invasive in vivo imaging of tumor-associated CD133/prominin. PMID: 21187924 Ref: Molecular identification and targeting of colorectal cancer stem cells. PMID: 21311095 |
Ref: Immunohistochemical analysis of tumour regression grade for rectal cancer after neoadjuvant chemoradiotherapy. PMID: 20718834 Ref: Bone morphogenetic protein 4 induces differentiation of colorectal cancer stem cells and increases their response to chemotherapy in mice. PMID: 20951698 Ref: Clinical significance of CD133 and hypoxia inducible factor-1alpha gene expression in rectal cancer after preoperative chemoradiotherapy. PMID: 20970309 Ref: Expression of CD176 (Thomsen-Friedenreich antigen) on lung, breast and liver cancer-initiating cells. PMID: 21070402 Ref: L1-mediated colon cancer cell metastasis does not require changes in EMT and cancer stem cell markers. PMID: 21123622 Ref: MicroRNA expression profile of colon cancer stem-like cells in HT29 adenocarcinoma cell line. PMID: 21130073 Ref: Colon cancer stem cells: implications in carcinogenesis. PMID: 21196254 Ref: The melatonin action on stromal stem cells within pericryptal area in colon cancer model under constant light. PMID: 21266165 Ref: Salinomycin selectively targets 'CD133+' cell subpopulations and decreases malignant traits in colorectal cancer lines. PMID: 21267784 Ref: [Changes in the biological behaviors of colon cancer cells under simulated hypoxia in vitro]. PMID: 21269976 Ref: Stem cells and their implications for colorectal cancer. PMID: 21293509 Ref: Inhibition of ataxia telangiectasia- and Rad3-related function abrogates the in vitro and in vivo tumorigenicity of human colon cancer cells through depletion of the CD133(+) tumor-initiating cell fraction. PMID: 21308861 Ref: Internal radiotherapy with copper-64-diacetyl-bis (N4-methylthiosemicarbazone) reduces CD133+ highly tumorigenic cells and metastatic ability of mouse colon carcinoma. PMID: 21315269 Ref: Is CD133 mRNA expression a prognostic factor in colorectal cancer? PMID: 21360712 Ref: Expression of cancer stem cell markers CD133 and CD44 in locoregional recurrence of rectal cancer. PMID: 21378329 Ref: Upregulated CD133 expression in tumorigenesis of colon cancer cells. PMID: 21412503 Ref: Clinicopathological significance and prognostic value of EphA3 and CD133 expression in colorectal carcinoma. PMID: 21415057 Ref: Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer. PMID: 21422427 Ref: Genome and transcriptome profiles of CD133-positive colorectal cancer cells. PMID: 21435437 Ref: A gene signature distinguishing CD133hi from CD133- colorectal cancer cells: essential role for EGR1 and downstream factors. PMID: 21436631 Ref: Proteome of human colon cancer stem cells: a comparative analysis. PMID: 21455326 Ref: LIN28B promotes colon cancer progression and metastasis. PMID: 21512136 Ref: Lipid phosphate phosphatase-3 regulates tumor growth via beta-catenin and CYCLIN-D1 signaling. PMID: 21569306 Ref: Schlafen-3 decreases cancer stem cell marker expression and autocrine/juxtacrine signaling in FOLFOX-resistant colon cancer cells. PMID: 21596996 Ref: [Selection and identification of specific-binding peptides for cancer stem cell surface marker CD133]. PMID: 21602120 Ref: LIN28B fosters colon cancer migration, invasion and transformation through let-7-dependent and -independent mechanisms. PMID: 21625210 Ref: SNAIL regulates interleukin-8 expression, stem cell-like activity, and tumorigenicity of human colorectal carcinoma cells. PMID: 21640118 Ref: Automated analysis of protein expression and gene amplification within the same cells of paraffin-embedded tumour tissue. PMID: 21656271 Ref: Isolation and characterization of spheroid cells from the HT29 colon cancer cell line. PMID: 21670985 Ref: Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030. PMID: 21694723 Ref: Mesenchymal stem cells promote formation of colorectal tumors in mice. PMID: 21699785 Ref: Highly enriched CD133(+)CD44(+) stem-like cells with CD133(+)CD44(high) metastatic subset in HCT116 colon cancer cells. PMID: 21750907 Ref: Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells. PMID: 21774804 Ref: Is CD133 a biomarker for cancer stem cells of colorectal cancer and brain tumors? A meta-analysis. PMID: 21786247 Ref: Pretreatment CD133 and cyclooxygenase-2 expression as the predictive markers of the pathological effect of chemoradiotherapy in rectal cancer patients. PMID: 21825889 Ref: Identification of Endothelin-1 and NR4A2 as CD133-regulated genes in colon cancer cells. PMID: 21826669 Ref: [Expressions of OCT4 and CD133 and their correlation in colonic cancer]. PMID: 21868340 Ref: Biomarkers of anti-angiogenic therapy in metastatic colorectal cancer (mCRC): original data and review of the literature. PMID: 21964893 Ref: The importance of the stem cell marker prominin-1/CD133 in the uptake of transferrin and in iron metabolism in human colon cancer Caco-2 cells. PMID: 21966538 Ref: APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis. PMID: 21985787 Ref: [Role of CD44(+)/ESA(+) in sorting colonic cancer stem cells]. PMID: 22116729 Ref: Colorectal cancer stem cell: a potential therapeutic target. PMID: 22126725 Ref: Differential CD133 expression pattern during mouse colon tumorigenesis. PMID: 22199291 Ref: CD133, OCT4, and NANOG in ulcerative colitis-associated colorectal cancer. PMID: 22848268 Ref: Cancer stem cell-related factors are associated with the efficacy of pre-operative chemoradiotherapy for locally advanced rectal cancer. PMID: 22977526 Ref: Overexpression of CYP3A4 in a COLO 205 Colon Cancer Stem Cell Model in vitro. PMID: 24212669 |
Ref: CD133(-) cells, derived from a single human colon cancer cell line, are more resistant to 5-fluorouracil (FU) than CD133(+) cells, dependent on the beta1-integrin signaling. PMID: 21601882 Ref: Prognostic value of putative circulating cancer stem cells in patients undergoing hepatic resection for colorectal liver metastasis. PMID: 22071867 Ref: CXCR4/CXCL12 expression profile is associated with tumor microenvironment and clinical outcome of liver metastases of colorectal cancer. PMID: 22075627 Ref: Effect of EpCAM, CD44, CD133 and CD166 expression on patient survival in tumours of the ampulla of Vater. PMID: 22130902 Ref: Preclinical evaluation of Mab CC188 for ovarian cancer imaging. PMID: 22130973 Ref: CD133+ colon cancer cells are more interactive with the tumor microenvironment than CD133- cells. PMID: 22157717 Ref: Silibinin suppresses the maintenance of colorectal cancer stem-like cells by inhibiting PP2A/AKT/mTOR pathways. PMID: 22213051 Ref: Targeting colorectal cancer stem cells with inducible caspase-9. PMID: 22223359 Ref: Immunohistochemical detection of CD133 is associated with tumor regression grade after chemoradiotherapy in rectal cancer. PMID: 22246526 Ref: Combined CD133/CD44 expression as a prognostic indicator of disease-free survival in patients with colorectal cancer. PMID: 22250106 Ref: Prognostic significance of CTCs and CSCs of tumor drainage vein blood in Dukes' stage B and C colorectal cancer patients. PMID: 22267181 Ref: A simple immunohistochemical algorithm predicts the risk of distant metastases in right-sided colon cancer. PMID: 22276605 Ref: Cultivation and identification of colon cancer stem cell-derived spheres from the Colo205 cell line. PMID: 22310487 Ref: Ascl2 knockdown results in tumor growth arrest by miRNA-302b-related inhibition of colon cancer progenitor cells. PMID: 22384170 Ref: CD133 as a target for colon cancer. PMID: 22385077 Ref: Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell marker. PMID: 22433494 Ref: Establishment of human ovarian serous carcinomas cell lines in serum free media. PMID: 22445873 Ref: Increased CD133 expression after preoperative chemoradiotherapy in rectal cancers other than mucin-rich tumors. PMID: 22453233 Ref: Mutations in the Ras-Raf Axis underlie the prognostic value of CD133 in colorectal cancer. PMID: 22496204 Ref: Downregulation of Prominin 1/CD133 expression in colorectal cancer by NSAIDs following short-term preoperative treatment. PMID: 22552364 Ref: Nanog: a potential biomarker for liver metastasis of colorectal cancer. PMID: 22562535 Ref: Biological significance of tumor budding at the invasive front of human colorectal carcinoma cells. PMID: 22569829 Ref: Protein cross-talk in CD133+ colon cancer cells indicates activation of the Wnt pathway and upregulation of SRp20 that is potentially involved in tumorigenicity. PMID: 22623141 Ref: A Pilot Study Assessing the Potential Role of non-CD133 Colorectal Cancer Stem Cells as Biomarkers. PMID: 22670157 Ref: Suppression of colorectal cancer metastasis by nigericin through inhibition of epithelial-mesenchymal transition. PMID: 22690072 Ref: Gene expression profiles of tumor regression grade in locally advanced rectal cancer after neoadjuvant chemoradiotherapy. PMID: 22711167 Ref: Cytoplasmic CD133 expression is a reliable prognostic indicator of tumor regression after neoadjuvant concurrent chemoradiotherapy in patients with rectal cancer. PMID: 22739652 Ref: Proliferation state and polo-like kinase1 dependence of tumorigenic colon cancer cells. PMID: 22753241 Ref: Expression of CD133 in SW620 colorectal cancer cells is modulated by the microenvironment. PMID: 22807964 Ref: Increased expression of CD133 is a strong predictor of poor outcome in stage I colorectal cancer patients. PMID: 22856425 Ref: CD133 marks for colorectal adenocarcinoma. PMID: 22870594 Ref: CD133(+)CXCR4(+) colon cancer cells exhibit metastatic potential and predict poor prognosis of patients. PMID: 22871210 Ref: Evaluation of CD44 and CD133 as cancer stem cell markers for colorectal cancer. PMID: 22895640 Ref: Characterization of the conversion between CD133+ and CD133- cells in colon cancer SW620 cell line. PMID: 22954703 Ref: Increased expression of CD133 and reduced dystroglycan expression are strong predictors of poor outcome in colon cancer patients. PMID: 22964035 Ref: Rapid re-expression of CD133 protein in colorectal cancer cell lines in vitro and in vivo. PMID: 22964855 Ref: Monoclonal antibodies against Lgr5 identify human colorectal cancer stem cells. PMID: 22969042 Ref: Clinical significance of radiation-induced CD133 expression in residual rectal cancer cells after chemoradiotherapy. PMID: 22969903 Ref: Co-expression of CXCR4 and CD133 proteins is associated with poor prognosis in stage II-III colon cancer patients. PMID: 22970002 Ref: Proteomic profiling of tumor-initiating cells in HT-29 human colorectal cancer cells. PMID: 22995320 Ref: miRNA expression profile of colon cancer stem cells compared to non-stem cells using the SW1116 cell line. PMID: 23007737 Ref: [Association of CD133 expression and sensitivity of rectal cancer to preoperative radiotherapy]. PMID: 23099908 Ref: Cell cycle analysis of the CD133(+) and CD133(-) cells isolated from human colorectal cancer. PMID: 23174722 Ref: Survival of cancer stem cells under hypoxia and serum depletion via decrease in PP2A activity and activation of p38-MAPKAPK2-Hsp27. PMID: 23185379 Ref: CD133+, CD166+CD44+, and CD24+CD44+ phenotypes fail to reliably identify cell populations with cancer stem cell functional features in established human colorectal cancer cell lines. PMID: 23197865 Ref: Antiproliferative effects of fluoxetine on colon cancer cells and in a colonic carcinogen mouse model. PMID: 23209640 Ref: Prognostic role of CD133 expression in colorectal cancer: a meta-analysis. PMID: 23216926 Ref: [Usefulness of CTCs in tumor drainage vein blood as a biomarker for prognosis in colorectal cancer patients with Dukes' stage B and C]. PMID: 23267879 |
Ref: Pharmacogenetic profiling of CD133 is associated with response rate (RR) and progression-free survival (PFS) in patients with metastatic colorectal cancer (mCRC), treated with bevacizumab-based chemotherapy. PMID: 22231565 Ref: Enrichment of CD133-expressing cells in rectal cancers treated with preoperative radiochemotherapy is an independent marker for metastasis and survival. PMID: 22736392 Ref: Co-expression of CD133(+)/CD44(+) in human colon cancer and liver metastasis. PMID: 22740326 Ref: Transcriptional profiling identifies genes induced by hepatocyte-derived extracellular matrix in metastatic human colorectal cancer cell lines. PMID: 22930170 Ref: Colon cancer stem cells resist antiangiogenesis therapy-induced apoptosis. PMID: 23017941 Ref: CD66c is a novel marker for colorectal cancer stem cell isolation, and its silencing halts tumor growth in vivo. PMID: 23027178 Ref: Isolation and characterization of calcium sensing receptor null cells: a highly malignant and drug resistant phenotype of colon cancer. PMID: 23055106 Ref: New Insights into the CD133 (Prominin-1) Expression in Mouse and Human Colon Cancer Cells. PMID: 23161081 Ref: CD133 affects the invasive ability of HCT116 cells by regulating TIMP-2. PMID: 23195431 Ref: Celecoxib downregulates CD133 expression through inhibition of the Wnt signaling pathway in colon cancer cells. PMID: 23245395 Ref: Leucine-rich repeat-containing G protein-coupled receptor 5 expression in ductular reactions after chemotherapy for metastatic colorectal cancer. PMID: 23332089 Ref: Clinical implications of periostin in the liver metastasis of colorectal cancer. PMID: 23347152 Ref: ST6Gal-I protein expression is upregulated in human epithelial tumors and correlates with stem cell markers in normal tissues and colon cancer cell lines. PMID: 23358684 Ref: Endothelial cells promote the colorectal cancer stem cell phenotype through a soluble form of Jagged-1. PMID: 23375636 Ref: CD133 expression and the prognosis of colorectal cancer: a systematic review and meta-analysis. PMID: 23409180 Ref: Kruppel-like factor 4 acts as an oncogene in colon cancer stem cell-enriched spheroid cells. PMID: 23418515 Ref: The stem cell marker CD133 is highly expressed in sessile serrated adenoma and its borderline variant compared with hyperplastic polyp. PMID: 23436931 Ref: A small molecule (pluripotin) as a tool for studying cancer stem cell biology: proof of concept. PMID: 23437320 Ref: Automatic cell cloning assay for determining the clonogenic capacity of cancer and cancer stem-like cells. PMID: 23450810 Ref: Association of gankyrin and stemness factor expression in human colorectal cancer. PMID: 23508981 Ref: CD133 expression is not an independent prognostic factor in stage II and III colorectal cancer but may predict the better outcome in patients with adjuvant therapy. PMID: 23537343 Ref: Prognostic value of changes in the expression of stem cell markers in the peripheral blood of patients with colon cancer. PMID: 23545848 Ref: Photochemical internalization (PCI) of immunotoxins targeting CD133 is specific and highly potent at femtomolar levels in cells with cancer stem cell properties. PMID: 23567040 Ref: Prognostic role of p53 messenger ribonucleic acid expression in patients after curative resection for stage I to III colorectal cancer: association with colon cancer stem cell markers. PMID: 23571142 Ref: Response to stress in early tumor colonization modulates switching of CD133-positive and CD133-negative subpopulations in a human metastatic colon cancer cell line, SW620. PMID: 23577199 Ref: CD133 is a selective marker of CRC? PMID: 23584268 Ref: Proteome profiling of exosomes derived from human primary and metastatic colorectal cancer cells reveal differential expression of key metastatic factors and signal transduction components. PMID: 23585443 Ref: MiR-142-3p functions as a tumor suppressor by targeting CD133, ABCG2, and Lgr5 in colon cancer cells. PMID: 23619912 Ref: CD133: a cancer stem cells marker, is used in colorectal cancers. PMID: 23674867 Ref: CD49f-positive cell population efficiently enriches colon cancer-initiating cells. PMID: 23708747 Ref: Cytometric profiling of CD133+ cells in human colon carcinoma cell lines identifies a common core phenotype and cell type-specific mosaics. PMID: 23709346 Ref: Biochemical and biological characterization of exosomes containing prominin-1/CD133. PMID: 23767874 Ref: CD 133+ and CXCR4+ colon cancer cells as a marker for lymph node metastasis. PMID: 23777983 Ref: [CD133(+) Colo205 colorectal cancer cells express high levels of ALDH1 in serum-free culture]. PMID: 23803205 Ref: Fibronectin extra domain A (EDA) sustains CD133(+)/CD44(+) subpopulation of colorectal cancer cells. PMID: 23811539 Ref: hypoxia-inducible factors activate CD133 promoter through ETS family transcription factors. PMID: 23840432 Ref: Omega-3 eicosapentaenoic acid decreases CD133 colon cancer stem-like cell marker expression while increasing sensitivity to chemotherapy. PMID: 23874993 Ref: Inhibition of the transcription factor Sp1 suppresses colon cancer stem cell growth and induces apoptosis in vitro and in nude mouse xenografts. PMID: 23877322 Ref: Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species. PMID: 23916687 Ref: Two-stage hepatectomy after autologous CD133+ stem cells administration: a case report. PMID: 23941680 Ref: [Expression of molecular markers detected by immunohistochemistry and risk of lymph node metastasis in stage T1 and T2 colorecrectal cancers]. PMID: 23985256 Ref: [Identification of "side population" associated with cancer stem cells by flow cytometry with violet laser]. PMID: 23987071 Ref: Water bath hyperthermia reduces stemness of colon cancer cells. PMID: 24028900 Ref: SNAIL and miR-34a feed-forward regulation of ZNF281/ZBP99 promotes epithelial-mesenchymal transition. PMID: 24185900 Ref: Effects of metformin on CD133+ colorectal cancer cells in diabetic patients. PMID: 24278407 Ref: [Application of genome-wide genechip for screening and identifying genes related to CD133(+)CD200(+) colorectal cancer stem cells]. PMID: 24369246 |
Ref: Differential expression of CD133 based on microsatellite instability status in human colorectal cancer. PMID: 23065858 Ref: Pretreatment expression of 13 molecular markers as a predictor of tumor responses after neoadjuvant chemoradiation in rectal cancer. PMID: 23787217 Ref: Nonsteroidal anti-inflammatory drugs suppress cancer stem cells via inhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer. PMID: 23852449 Ref: Bufalin inhibits the differentiation and proliferation of human osteosarcoma cell line hMG63-derived cancer stem cells. PMID: 24006225 Ref: Differential clinical benefits of 5-fluorouracil-based adjuvant chemotherapy for patients with stage III colorectal cancer according to CD133 expression status. PMID: 24244031 Ref: TMPRSS4 correlates with colorectal cancer pathological stage and regulates cell proliferation and self-renewal ability. PMID: 24335200 Ref: CD133 and CD133-regulated nucleophosmin linked to 5-fluorouracil susceptibility in human colon cancer cell line SW620. PMID: 24339132 Ref: Expression and prognostic value of tumor stem cell markers ALDH1 and CD133 in colorectal carcinoma. PMID: 24396478 Ref: Role of oncogenic K-Ras in cancer stem cell activation by aberrant Wnt/beta-catenin signaling. PMID: 24491301 Ref: Hes1 is involved in the self-renewal and tumourigenicity of stem-like cancer cells in colon cancer. PMID: 24492635 Ref: Patients with CD133-negative colorectal liver metastasis have a poor prognosis after hepatectomy. PMID: 24554065 Ref: Prognostic value of stem cell quantification in stage II colon cancer. PMID: 24586330 Ref: Overexpression of B7-H3 in CD133+ colorectal cancer cells is associated with cancer progression and survival in human patients. PMID: 24630518 Ref: P21 and CD166 as predictive markers of poor response and outcome after fluorouracil-based chemoradiotherapy for the patients with rectal cancer. PMID: 24708484 Ref: Evaluation of cancer stem cell markers CD133, CD44, CD24: association with AKT isoforms and radiation resistance in colon cancer cells. PMID: 24760019 Ref: Comparison of nucleostemin gene expression in CD133+ and CD133- cell population in colon cancer cell line HT29. PMID: 24762489 Ref: Brief report: impaired in vivo neovascularization capacity of endothelial progenitor cells in patients with systemic sclerosis. PMID: 24782187 Ref: LGR5 is required for the maintenance of spheroid-derived colon cancer stem cells. PMID: 24789370 Ref: [Effect of CD133(+) cells on the radiosensitivity of rectal cancer cells]. PMID: 24796457 Ref: ZNF281/ZBP-99: a new player in epithelial-mesenchymal transition, stemness, and cancer. PMID: 24838609 Ref: Immunohistochemical detection of cancer stem cell related markers CD44 and CD133 in metastatic colorectal cancer patients. PMID: 24864242 Ref: Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells. PMID: 24905352 Ref: Establishment of highly tumorigenic human colorectal cancer cell line (CR4) with properties of putative cancer stem cells. PMID: 24921652 Ref: Prognostic significance of CD44 variant 2 upregulation in colorectal cancer. PMID: 24921913 Ref: Characterization of side population cells isolated from the colon cancer cell line SW480. PMID: 24926880 Ref: CD133/CD166/Ki-67 triple immunofluorescence assessment for putative cancer stem cells in colon carcinoma. PMID: 24949608 Ref: Evaluation of prognostic significance of circulating tumor cells detection in rectal cancer patients treated with preoperative radiotherapy: prospectively collected material data. PMID: 25006584 Ref: Prognostic impact of MGMT promoter methylation and MGMT and CD133 expression in colorectal adenocarcinoma. PMID: 25015560 Ref: Curcumin suppresses crosstalk between colon cancer stem cells and stromal fibroblasts in the tumor microenvironment: potential role of EMT. PMID: 25238234 Ref: Spinophilin expression determines cellular growth, cancer stemness and 5-flourouracil resistance in colorectal cancer. PMID: 25261368 Ref: Human CD133-positive hematopoietic progenitor cells initiate growth and metastasis of colorectal cancer cells. PMID: 25269803 Ref: Transcriptome analysis of CD133-positive stem cells and prognostic value of survivin in colorectal cancer. PMID: 25331798 Ref: Preoperative low dose NSAID treatment influences the genes for stemness, growth, invasion and metastasis in colorectal cancer. PMID: 25340937 Ref: Comparison of putative circulating cancer stem cell detection between the hepatic portal system and peripheral blood in colorectal cancer patients. PMID: 25368848 Ref: ABCG2-meditated multidrug resistance and tumor-initiating capacity of side population cells from colon cancer. PMID: 25427584 Ref: CD133-positive tumor cell content is a predictor of early recurrence in colorectal cancer. PMID: 25436124 Ref: CD133 expression is correlated with poor prognosis in colorectal cancer. PMID: 25436343 Ref: Prom1 function in development, intestinal inflammation, and intestinal tumorigenesis. PMID: 25452936 Ref: Colon cancer: cancer stem cells markers, drug resistance and treatment. PMID: 25458789 Ref: High levels of SIRT1 expression enhance tumorigenesis and associate with a poor prognosis of colorectal carcinoma patients. PMID: 25500546 Ref: A metabolic signature of colon cancer initiating cells. PMID: 25571056 Ref: Stem cells, colorectal cancer and cancer stem cell markers correlations. PMID: 25729599 |
Ref: Receptor-type protein tyrosine phosphatase kappa directly dephosphorylates CD133 and regulates downstream AKT activation. PMID: 24882578 Ref: Fe-bLf nanoformulation targets survivin to kill colon cancer stem cells and maintains absorption of iron, calcium and zinc. PMID: 25017148 Ref: Lipid droplets: a new player in colorectal cancer stem cells unveiled by spectroscopic imaging. PMID: 25186497 Ref: COX-2- and endoplasmic reticulum stress-independent induction of ULBP-1 and enhancement of sensitivity to NK cell-mediated cytotoxicity by celecoxib in colon cancer cells. PMID: 25218028 Ref: ALDH1 is a prognostic factor for patients treated with neoadjuvant chemoradiotherapy and radical resection for stage III rectal cancer. PMID: 25270363 Ref: The requirement for freshly isolated human colorectal cancer (CRC) cells in isolating CRC stem cells. 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