Primary Site >> Colorectal Cancer

Gene >> PRNP

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Ref: Proteolytic processing of the ovine prion protein in cell cultures.
PMID: 16182247
Ref: Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer.
PMID: 17615082
Ref: POLR2F, ATP6V0A1 and PRNP expression in colorectal cancer: new molecules with prognostic significance?
PMID: 18505059
Ref: Antibodies to prion protein inhibit human colon cancer cell growth.
PMID: 19521145
Ref: Prion protein expression and the M129V polymorphism of the PRNP gene in patients with colorectal cancer.
PMID: 20564346
Ref: Cellular prion protein promotes glucose uptake through the Fyn-HIF-2alpha-Glut1 pathway to support colorectal cancer cell survival.
PMID: 21265952
Ref: Resistance against apoptosis by the cellular prion protein is dependent on its glycosylation status in oral HSC-2 and colon LS 174T cancer cells.
PMID: 21439722
Ref: Cell surface proteomics identifies glucose transporter type 1 and prion protein as candidate biomarkers for colorectal adenoma-to-carcinoma progression.
PMID: 21890811
Ref: Cellular prion protein accelerates colorectal cancer metastasis via the Fyn-SP1-SATB1 axis.
PMID: 22972305
Ref: CD44-positive cancer stem cells expressing cellular prion protein contribute to metastatic capacity in colorectal cancer.
PMID: 23418321
Ref: Cellular prion protein contributes to LS 174T colon cancer cell carcinogenesis by increasing invasiveness and resistance against doxorubicin-induced apoptosis.
PMID: 25983001
Ref: Prion protein binding to HOP modulates the migration and invasion of colorectal cancer cells.
PMID: 27112151
Ref: Silencing Prion Protein in HT29 Human Colorectal Cancer Cells Enhances Anticancer Response to Fucoidan.
PMID: 27630281
Ref: Cellular prion protein (PrP(C)) in the development of Merlin-deficient tumours.
PMID: 28692055
Ref: Role of HSPA1L as a cellular prion protein stabilizer in tumor progression via HIF-1alpha/GP78 axis.
PMID: 28759037
Ref: Prion Protein Family Contributes to Tumorigenesis via Multiple Pathways.
PMID: 29052140
Ref: Cellular Prion Protein Enhances Drug Resistance of Colorectal Cancer Cells via Regulation of a Survival Signal Pathway.
PMID: 28822989
Ref: Cellular prion protein and gamma-synuclein overexpression in LS 174T colorectal cancer cell drives endothelial proliferation-to-differentiation switch.
PMID: 29527422
Ref: Melatonin Promotes Apoptosis of Colorectal Cancer Cells via Superoxide-mediated ER Stress by Inhibiting Cellular Prion Protein Expression.
PMID: 29970517
Ref: Melatonin and 5-fluorouracil co-suppress colon cancer stem cells by regulating cellular prion protein-Oct4 axis.
PMID: 30091203