Primary Site >> Stomach Cancer

Gene >> PRMT5

  • 2005
  • 2016
  • 2017
  • 2018
Ref: Identification of gastric cancer-related genes using a cDNA microarray containing novel expressed sequence tags expressed in gastric cancer cells.
PMID: 15701830
Ref: Protein arginine methyltransferase 5 is associated with malignant phenotype and peritoneal metastasis in gastric cancer.
PMID: 27315569
Ref: Arginine methyltransferase inhibitor 1 inhibits gastric cancer by downregulating eIF4E and targeting PRMT5.
PMID: 28987382
Ref: Protein arginine methyltransferase 5-mediated epigenetic silencing of IRX1 contributes to tumorigenicity and metastasis of gastric cancer.
PMID: 29802960
Ref: LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity.
PMID: 30034588