Primary Site >> Pancreatic Cancer
Gene >> PRKDC
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Ref: Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2. PMID: 11196174 |
Ref: Nonhomologous end joining is essential for cellular resistance to the novel antitumor agent, beta-lapachone. PMID: 17638905 |
Ref: Mutational analysis of thirty-two double-strand DNA break repair genes in breast and pancreatic cancers. PMID: 18281469 |
Ref: Non-invasive fluorescent-protein imaging of orthotopic pancreatic-cancer-patient tumorgraft progression in nude mice. PMID: 22843874 |
Ref: DNA-PKcs is important for Akt activation and gemcitabine resistance in PANC-1 pancreatic cancer cells. PMID: 25152407 |
Ref: Isolation of Pancreatic Cancer Cells from a Patient-Derived Xenograft Model Allows for Practical Expansion and Preserved Heterogeneity in Culture. PMID: 27102771 Ref: Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancer. PMID: 27621574 |
Ref: Patient-derived xenografts of gastrointestinal cancers are susceptible to rapid and delayed B-lymphoproliferation. PMID: 27935045 Ref: Orthotopic Patient-Derived Pancreatic Cancer Xenografts Engraft Into the Pancreatic Parenchyma, Metastasize, and Induce Muscle Wasting to Recapitulate the Human Disease. PMID: 28609371 Ref: Caveolin-1 is involved in DNA damage and repair signaling in X-irradiated Chang liver cells. PMID: 29270591 Ref: Radiosensitization of the PI3K inhibitor HS-173 through reduction of DNA damage repair in pancreatic cancer. PMID: 29348875 |
Ref: The radiotherapy-sensitization effect of cantharidin: Mechanisms involving cell cycle regulation, enhanced DNA damage, and inhibited DNA damage repair. PMID: 30201439 |