Primary Site >> Colorectal Cancer
Gene >> PRKCB
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Ref: Overexpression of protein kinase C in HT29 colon cancer cells causes growth inhibition and tumor suppression. PMID: 2388620 |
Ref: Expression of putative anticancer targets in familial adenomatous polyposis and its association with the APC mutation status. PMID: 11713587 |
Ref: LY317615 decreases plasma VEGF levels in human tumor xenograft-bearing mice. PMID: 14593497 Ref: Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway. PMID: 15037605 Ref: Protein kinase CbetaII regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo. PMID: 15322124 |
Ref: Bile acid deoxycholate induces differential subcellular localisation of the PKC isoenzymes beta 1, epsilon and delta in colonic epithelial cells in a sodium butyrate insensitive manner. PMID: 15645414 Ref: The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts. PMID: 16103100 |
Ref: Neurotensin phosphorylates GSK-3alpha/beta through the activation of PKC in human colon cancer cells. PMID: 16984735 |
Ref: Protein kinase C betaII and PKCiota/lambda: collaborating partners in colon cancer promotion and progression. PMID: 19147581 Ref: Protein kinase Cbeta is an effective target for chemoprevention of colon cancer. PMID: 19221092 |
Ref: Epithelial-to-mesenchymal transition and oncogenic Ras expression in resistance to the protein kinase Cbeta inhibitor enzastaurin in colon cancer cells. PMID: 20406951 Ref: Protein kinase C-beta gene variants, pathway activation, and enzastaurin activity in lung cancer. PMID: 20439192 |
Ref: Identification of microRNAs regulated by isothiocyanates and association of polymorphisms inside their target sites with risk of sporadic colorectal cancer. PMID: 23441612 Ref: Brucine suppresses colon cancer cells growth via mediating KDR signalling pathway. PMID: 23905676 |
Ref: Screening of hub genes and pathways in colorectal cancer with microarray technology. PMID: 24504536 |
Ref: Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor. PMID: 25619690 Ref: Apoptin interacts with and regulates the activity of protein kinase C beta in cancer cells. PMID: 25828882 |
Ref: Regulation of protein kinase CK2 catalytic activity by protein kinase C and phospholipase D2. PMID: 26703243 |
Ref: Altered expression profiles of circular RNA in colorectal cancer tissues from patients with lung metastasis. PMID: 29039473 |
Ref: Polyphenol extracts from dried sugarcane inhibit inflammatory mediators in an in vitro colon cancer model. PMID: 29432917 Ref: The MAPK-Signaling Pathway in Colorectal Cancer: Dysregulated Genes and Their Association With MicroRNAs. PMID: 29636593 |