Primary Site >> Colorectal Cancer
Gene >> PRIMA1
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Ref: Genetic susceptibility for specific cancers. Medical liability of the clinician. PMID: 10630182 |
Ref: Selective induction of apoptosis in mutant p53 premalignant and malignant cancer cells by PRIMA-1 through the c-Jun-NH2-kinase pathway. PMID: 15956247 |
Ref: Small-molecule modulators of p53 family signaling and antitumor effects in p53-deficient human colon tumor xenografts. PMID: 16835297 Ref: Cholinesterases are down-expressed in human colorectal carcinoma. PMID: 16909200 |
Ref: Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion. PMID: 17130833 |
Ref: PRIMA-1met (APR-246) inhibits growth of colorectal cancer cells with different p53 status through distinct mechanisms. PMID: 26452133 Ref: DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer. PMID: 26482433 |
Ref: PRIMA-1Met suppresses colorectal cancer independent of p53 by targeting MEK. PMID: 27806324 Ref: Hypoxic resistance of KRAS mutant tumor cells to 3-Bromopyruvate is counteracted by Prima-1 and reversed by N-acetylcysteine. PMID: 27863474 |
Ref: Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples. PMID: 28753106 |
Ref: Blood Collection and Cell-Free DNA Isolation Methods Influence the Sensitivity of Liquid Biopsy Analysis for Colorectal Cancer Detection. PMID: 29374860 |