Primary Site >> Stomach Cancer

Gene >> PPP1R1B

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Ref: MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cystein domain.
PMID: 12739007
Ref: Overexpression of the 32-kilodalton dopamine and cyclic adenosine 3',5'-monophosphate-regulated phosphoprotein in common adenocarcinomas.
PMID: 14508844
Ref: Coamplified and overexpressed genes at ERBB2 locus in gastric cancer.
PMID: 14991576
Ref: Evolutionary recombination hotspot around GSDML-GSDM locus is closely linked to the oncogenomic recombination hotspot around the PPP1R1B-ERBB2-GRB7 amplicon.
PMID: 15010812
Ref: DARPP-32 expression arises after a phase of dysplasia in oesophageal squamous cell carcinoma.
PMID: 15188007
Ref: Reversal of multidrug resistance of vincristine-resistant gastric adenocarcinoma cells through up-regulation of DARPP-32.
PMID: 17470401
Ref: DARPP-32 mediates multidrug resistance of gastric cancer through regulation of P-gp and ZNRD1.
PMID: 18058465
Ref: Reversal of multidrug resistance of adriamycin-resistant gastric adenocarcinoma cells through the up-regulation of DARPP-32.
PMID: 17492506
Ref: t-Darpp promotes cancer cell survival by up-regulation of Bcl2 through Akt-dependent mechanism.
PMID: 18199533
Ref: Integrated gene copy number and expression microarray analysis of gastric cancer highlights potential target genes.
PMID: 18506690
Ref: Preparation of a novel monoclonal antibody specific to DARPP-32.
PMID: 20715994
Ref: Resistance to TRAIL is mediated by DARPP-32 in gastric cancer.
PMID: 22589394
Ref: PPP1R1B-STARD3 chimeric fusion transcript in human gastric cancer promotes tumorigenesis through activation of PI3K/AKT signaling.
PMID: 24276243
Ref: Association analysis of ERBB2 amplicon genetic polymorphisms and STARD3 expression with risk of gastric cancer in the Chinese population.
PMID: 24291029
Ref: Regulation of CD44E by DARPP-32-dependent activation of SRp20 splicing factor in gastric tumorigenesis.
PMID: 26119931