Primary Site >> Colorectal Cancer
Gene >> PPARGC1A
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Ref: Peroxisome proliferator-activated receptors (PPARs) and associated transcription factors in colon cancer: reduced expression of PPARgamma-coactivator 1 (PGC-1). PMID: 14670614 |
Ref: Validation of the use of DNA pools and primer extension in association studies of sporadic colorectal cancer for selection of candidate SNPs. PMID: 16395669 |
Ref: A novel steroidal inhibitor of estrogen-related receptor alpha (ERR alpha). PMID: 20513360 |
Ref: Simulated colon fiber metabolome regulates genes involved in cell cycle, apoptosis, and energy metabolism in human colon cancer cells. PMID: 21667160 Ref: Bax is necessary for PGC1alpha pro-apoptotic effect in colorectal cancer cells. PMID: 21862870 |
Ref: p21(WAF(1)/C(1)P(1)) deficiency induces mitochondrial dysfunction in HCT116 colon cancer cells. PMID: 23211592 Ref: Mitochondria and tumor progression in ulcerative colitis. PMID: 23852949 |
Ref: Overexpression of PGC1alpha enhances cell proliferation and tumorigenesis of HEK293 cells through the upregulation of Sp1 and Acyl-CoA binding protein. PMID: 25585584 Ref: SIRT1/PGC1alpha-Dependent Increase in Oxidative Phosphorylation Supports Chemotherapy Resistance of Colon Cancer. PMID: 25779952 |
Ref: SIRT1 prevents hyperuricemia via the PGC-1alpha/PPARgamma-ABCG2 pathway. PMID: 27022940 Ref: [Effect of peroxisome proliferator-activated receptor-gamma coactivator-1alpha on metastasis and anoikis resistance in colorectal cancer]. PMID: 27531262 Ref: Cancer and Chemotherapy Contribute to Muscle Loss by Activating Common Signaling Pathways. PMID: 27807421 |
Ref: Molecular Portrait of Metastasis-Competent Circulating Tumor Cells in Colon Cancer Reveals the Crucial Role of Genes Regulating Energy Metabolism and DNA Repair. PMID: 28007957 Ref: Genetic variation in PPARGC1A may affect the role of diet-associated inflammation in colorectal carcinogenesis. PMID: 28051997 Ref: Metabolic reprogramming of the premalignant colonic mucosa is an early event in carcinogenesis. PMID: 28423551 Ref: Expression and role of nuclear receptor coregulators in colorectal cancer. PMID: 28740336 Ref: Aldose reductase inhibitor, fidarestat regulates mitochondrial biogenesis via Nrf2/HO-1/AMPK pathway in colon cancer cells. PMID: 28986187 Ref: Alterations in PGC1alpha expression levels are involved in colorectal cancer risk: a qualitative systematic review. PMID: 29121859 Ref: Expression of fatty acid synthase is regulated by PGC1alpha and contributes to increased cell proliferation. PMID: 29130104 Ref: The mitochondrial metabolic reprogramming agent trimetazidine as an 'exercise mimetic' in cachectic C26-bearing mice. PMID: 29130633 |
Ref: Identification of Estrogen-Related Receptor alpha Agonists in the Tox21 Compound Library. PMID: 29216352 Ref: CHTM1, a novel metabolic marker deregulated in human malignancies. PMID: 29371680 Ref: Peroxisome proliferator-activated receptor gamma coactivator-1alpha is a predictor of lymph node metastasis and poor prognosis in human colorectal cancer. PMID: 29566941 Ref: PGC-1alpha as a Biomarker of Physical Activity-Protective Effect on Colorectal Cancer. PMID: 29789344 Ref: Identification of Critical Genes and Five Prognostic Biomarkers Associated with Colorectal Cancer. PMID: 29973580 Ref: Cholesterol as an Endogenous ERRalpha Agonist: A New Perspective to Cancer Treatment. PMID: 30254608 |