Primary Site >> Stomach Cancer
Gene >> POU5F1
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Ref: Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: Transcriptional mechanisms of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, and diffuse-type gastric cancer. PMID: 17273778 Ref: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs. PMID: 17390031 Ref: Comparative integromics on JMJD1C gene encoding histone demethylase: conserved POU5F1 binding site elucidating mechanism of JMJD1C expression in undifferentiated ES cells and diffuse-type gastric cancer. PMID: 17549425 Ref: Integrative genomic analyses on HES/HEY family: Notch-independent HES1, HES3 transcription in undifferentiated ES cells, and Notch-dependent HES1, HES5, HEY1, HEY2, HEYL transcription in fetal tissues, adult tissues, or cancer. PMID: 17611704 |
Ref: Oct4, a novel marker for human gastric cancer. PMID: 19347886 |
Ref: Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors. PMID: 20043076 |
Ref: OCT4B1, a novel spliced variant of OCT4, is highly expressed in gastric cancer and acts as an antiapoptotic factor. PMID: 20824712 |
Ref: Role of the stemness factors sox2, oct3/4, and nanog in gastric carcinoma. PMID: 21227461 Ref: Inhibition of LDH-A by lentivirus-mediated small interfering RNA suppresses intestinal-type gastric cancer tumorigenicity through the downregulation of Oct4. PMID: 22429998 Ref: Upregulation and inhibition of the nuclear translocation of Oct4 during multistep gastric carcinogenesis. PMID: 22922943 Ref: Side population cells isolated from KATO III human gastric cancer cell line have cancer stem cell-like characteristics. PMID: 22969237 Ref: Expression profiling of stem cell-related genes in neoadjuvant-treated gastric cancer: a NOTCH2, GSK3B and beta-catenin gene signature predicts survival. PMID: 22970250 Ref: [Expression of OCT4 in gastric cancer cell lines and its significance]. PMID: 23387203 |
Ref: Not all side population cells contain cancer stem-like cells in human gastric cancer cell lines. PMID: 22878917 Ref: Orphan receptor TR3 is essential for the maintenance of stem-like properties in gastric cancer cells. PMID: 23043761 Ref: Spheroid body-forming cells in the human gastric cancer cell line MKN-45 possess cancer stem cell properties. PMID: 23229446 Ref: Characterization of cancer stem-like cells in the side population cells of human gastric cancer cell line MKN-45. PMID: 23463764 Ref: Primo vascular system and its potential role in cancer metastasis. PMID: 23852507 Ref: Significantly increased expression of OCT4 and ABCG2 in spheroid body-forming cells of the human gastric cancer MKN-45 cell line. PMID: 24137432 Ref: Effects of the hippo signaling pathway in human gastric cancer. PMID: 24175801 Ref: DNA damage in inflammation-related carcinogenesis and cancer stem cells. PMID: 24382987 |
Ref: RECK inhibits stemness gene expression and tumorigenicity of gastric cancer cells by suppressing ADAM-mediated Notch1 activation. PMID: 23881612 Ref: Molecular insight in gastric cancer induction: an overview of cancer stemness genes. PMID: 24078401 Ref: Roles of Wnt/beta-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment. PMID: 24481453 Ref: Specificity protein 1 expression contributes to Bcl-w-induced aggressiveness in glioblastoma multiforme. PMID: 24552705 Ref: Autophagy promotes the survival and development of tumors by participating in the formation of vasculogenic mimicry. PMID: 24626574 Ref: Influence of different hypoxia models on metastatic potential of SGC-7901 gastric cancer cells. PMID: 24729089 Ref: An epigenetic mechanism underlying doxorubicin induced EMT in the human BGC-823 gastric cancer cell. PMID: 24935383 Ref: OCT3/4 expression is correlated with the invasion of gastric carcinoma. PMID: 24959212 Ref: Yin Yang 1 is a target of microRNA-34 family and contributes to gastric carcinogenesis. PMID: 24970812 Ref: Coexpression of HMGA2 and Oct4 predicts an unfavorable prognosis in human gastric cancer. PMID: 25037576 |
Ref: The OCT4 pseudogene POU5F1B is amplified and promotes an aggressive phenotype in gastric cancer. PMID: 24362523 Ref: Synergic effect between 5fluorouracil and celecoxib on hypoxic gastric cancer cells. PMID: 25351347 Ref: Inhibitory effects and mechanism of 5-fluorouracil combined with celecoxib on human gastric cancer xenografts in nude mice. PMID: 25452783 Ref: Prognostic evaluation of Nanog, Oct4, Sox2, PCNA, Ki67 and E-cadherin expression in gastric cancer. PMID: 25491144 Ref: Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell. PMID: 25542229 Ref: A preliminary study of side population cells in human gastric cancer cell line HGC-27. PMID: 25773762 Ref: High expression of OCT4 is frequent and may cause undesirable treatment outcomes in patients with acute myeloid leukemia. PMID: 26152287 Ref: [Changes in the number of copies of genetic loci in gastric cancer]. PMID: 26299866 Ref: Evodiamine, a novel inhibitor of the Wnt pathway, inhibits the self-renewal of gastric cancer stem cells. PMID: 26497016 Ref: Tumorigenic hybrids between mesenchymal stem cells and gastric cancer cells enhanced cancer proliferation, migration and stemness. PMID: 26498753 |
Ref: Hypoxic Microenvironment Induces EMT and Upgrades Stem-Like Properties of Gastric Cancer Cells. PMID: 25601854 Ref: Identification of stem-like cells and clinical significance of candidate stem cell markers in gastric cancer. PMID: 26769843 Ref: Oct-4 is associated with gastric cancer progression and prognosis. PMID: 26869797 Ref: Helicobacter pylori upregulates Nanog and Oct4 via Wnt/beta-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer. PMID: 26940070 Ref: PlGF knockdown inhibited tumor survival and migration in gastric cancer cell via PI3K/Akt and p38MAPK pathways. PMID: 26968576 Ref: Functional and clinical significance of SALL4 in breast cancer. PMID: 27444278 Ref: Nanovesicle-mediated systemic delivery of microRNA-34a for CD44 overexpressing gastric cancer stem cell therapy. PMID: 27497057 Ref: Mel-18 negatively regulates stem cell-like properties through downregulation of miR-21 in gastric cancer. PMID: 27542229 Ref: Clinical significance of putative markers of cancer stem cells in gastric cancer: A retrospective cohort study. PMID: 27557490 Ref: Long Noncoding RNA ROR Regulates Proliferation, Invasion, and Stemness of Gastric Cancer Stem Cell. PMID: 27602437 Ref: High-fat diet feeding promotes stemness and precancerous changes in murine gastric mucosa mediated by leptin receptor signaling pathway. PMID: 27693038 Ref: LGR5 Is a Gastric Cancer Stem Cell Marker Associated with Stemness and the EMT Signature Genes NANOG, NANOGP8, PRRX1, TWIST1, and BMI1. PMID: 28033430 Ref: Nitrative and oxidative DNA damage in infection-related carcinogenesis in relation to cancer stem cells. PMID: 28050219 |
Ref: Different Genotype of rs3130932 Single Nucleotide Polymorphism Between Gastric Cancer Patients and Normal Subjects. PMID: 27573011 Ref: IL-17B activated mesenchymal stem cells enhance proliferation and migration of gastric cancer cells. PMID: 28145881 Ref: HMGA2 regulates CD44 expression to promote gastric cancer cell motility and sphere formation. PMID: 28337375 Ref: Anti-carcinogenic and anti-angiogenic properties of the extracts of Acorus calamus on gastric cancer cells. PMID: 28348970 Ref: Prognostic significance of KLF4 expression in gastric cancer. PMID: 28356964 Ref: USP22 maintains gastric cancer stem cell stemness and promotes gastric cancer progression by stabilizing BMI1 protein. PMID: 28415621 Ref: Gastric Cancer With Primitive Enterocyte Phenotype: An Aggressive Subgroup of Intestinal-type Adenocarcinoma. PMID: 28505005 Ref: siRNA-mediated knockdown of ID1 disrupts Nanog- and Oct-4-mediated cancer stem cell-likeness and resistance to chemotherapy in gastric cancer cells. PMID: 28529558 Ref: Differential expression of two genes Oct-4 and MUC5AC associates with poor outcome in patients with gastric cancer. PMID: 28762513 Ref: Reprogramming Antagonizes the Oncogenicity of HOXA13-Long Noncoding RNA HOTTIP Axis in Gastric Cancer Cells. PMID: 28782268 Ref: UBR2 Enriched in p53 Deficient Mouse Bone Marrow Mesenchymal Stem Cell-Exosome Promoted Gastric Cancer Progression via Wnt/beta-Catenin Pathway. PMID: 28895255 Ref: GLI2 induces PDGFRB expression and modulates cancer stem cell properties of gastric cancer. PMID: 28975979 |
Ref: Ibuprofen reduces cell proliferation through inhibiting Wnt/beta catenin signaling pathway in gastric cancer stem cells. PMID: 29512256 Ref: Isolation and identification of chemotherapy-enriched sphere-forming cells from a patient with gastric cancer. PMID: 29744869 Ref: KRAB zinc-finger protein 382 regulates epithelial-mesenchymal transition and functions as a tumor suppressor, but is silenced by CpG methylation in gastric cancer. PMID: 29956735 Ref: SOX4 contributes to TGF-beta-induced epithelial-mesenchymal transition and stem cell characteristics of gastric cancer cells. PMID: 30258935 |