Primary Site >> Esophagus Cancer

Gene >> POU5F1

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Ref: Activation of the esophagin promoter during esophageal epithelial cell differentiation.
PMID: 12036303
 Ref: Comparative genomics on mammalian Fgf3-Fgf4 locus.
PMID: 15942670
 Ref: Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus.
PMID: 18451249
 Ref: Oct3/4 and Sox2 are significantly associated with an unfavorable clinical outcome in human esophageal squamous cell carcinoma.
PMID: 19414369
 Ref: Esophageal cancer tumorspheres involve cancer stem-like populations with elevated aldehyde dehydrogenase enzymatic activity.
PMID: 22684859
Ref: OCT4 positively regulates Survivin expression to promote cancer cell proliferation and leads to poor prognosis in esophageal squamous cell carcinoma.
PMID: 23185410
Ref: Expression analysis of iPS cell - inductive genes in esophageal squamous cell carcinoma by tissue microarray.
PMID: 23225459
 Ref: The usefulness of three-dimensional cell culture in induction of cancer stem cells from esophageal squamous cell carcinoma cell lines.
PMID: 23602898
Ref: Physiological beta-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma.
PMID: 24073846
 Ref: Forthcoming prognostic markers for esophageal cancer: a systematic review and meta-analysis.
PMID: 24490044
Ref: Transcription factor OCT4 promotes cell cycle progression by regulating CCND1 expression in esophageal carcinoma.
PMID: 25128069
 Ref: Evaluating the miR-302b and miR-145 expression in formalin-fixed paraffin-embedded samples of esophageal squamous cell carcinoma.
PMID: 25773691
Ref: High expression of OCT4 is frequent and may cause undesirable treatment outcomes in patients with acute myeloid leukemia.
PMID: 26152287
 Ref: Transcriptional factor OCT4 promotes esophageal cancer metastasis by inducing epithelial-mesenchymal transition through VEGF-C/VEGFR-3 signaling pathway.
PMID: 29069758